Molecular Basis of Hypohidrotic Ectodermal Dysplasia: An Update

    August 2015 in “ Journal of Applied Genetics ”
    Wiesław H. Trzeciak, Ryszard Koczorowski
    Studysummary This review discusses recent insights into the molecular mechanisms of hypohidrotic ectodermal dysplasia linked to TNFα-related signaling pathway mutations but reports no new experimental results.
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    Research cited in this study 7

    1. A New Mutation Resulting in the Truncation of the TRAF6-Interacting Domain of XEDAR: A Possible Novel Cause of Hypohidrotic Ectodermal Dysplasia Journal of Medical Genetics · 2012
    2. Investigation of the Male Pattern Baldness Major Genetic Susceptibility Loci AR/EDA2R and 20p11 in Female Pattern Hair Loss British Journal of Dermatology · 2012
    3. A Replication Study Confirmed the EDAR Gene to Be a Major Contributor to Population Differentiation Regarding Head Hair Thickness in Asia Human genetics · 2008
    4. EDA2R Is Associated With Androgenetic Alopecia Journal of Investigative Dermatology · 2008
    5. Significant Correction of Disease After Postnatal Administration of Recombinant Ectodysplasin A in Canine X-Linked Ectodermal Dysplasia American Journal of Human Genetics · 2007
    6. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    7. Myodegeneration in EDA-A2 Transgenic Mice Is Prevented by XEDAR Deficiency Molecular and Cellular Biology · 2004

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