Marie-Unna Hereditary Hypotrichosis: Case Report and Review of the Literature

March 2011 in “ Pediatric dermatology ”

Joshua O. Podjasek, Jennifer L. Hand

TLDR An 18-year-old girl was diagnosed with a rare hereditary hair loss condition, despite no family history.

An 18-year-old girl experienced progressively worsening hair thinning and loss since puberty, diagnosed as Marie‐Unna hereditary hypotrichosis, a rare autosomal dominant hereditary hair loss condition. Despite no family history of similar hair loss, her clinical history, physical examination, and pathology results confirmed the diagnosis, marking the first reported case of this condition in a previously unaffected family.

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research Office Diagnosis of Hair Shaft Defects

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research A Distinct Gene Close to the Hairless Locus on Chromosome 8p Underlies Hereditary Marie Unna Type Hypotrichosis in a German Family

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The article concludes that understanding the causes of hair loss and using continuous treatments like minoxidil and finasteride can help manage it, despite potential side effects.