Alopecia in Congenital Hidrotic Ectodermal Dysplasia Responding to Treatment with a Combination of Topical Minoxidil and Tretinoin

    January 2009 in “ International Journal of Dermatology ”
    Shubha Melkote, Rachita Dhurat, Anjali A. Palav, Hemangi Jerajani
    Image of study
    TLDR Hair loss in Clouston's syndrome improved with minoxidil and tretinoin treatment.
    This article reports on a case of a 6-year-old boy with congenital hidrotic ectodermal dysplasia, also known as Clouston's syndrome, who had alopecia. The patient was treated with a combination of topical minoxidil and tretinoin, resulting in a threefold increase in hair density on the scalp after six months of therapy. The authors propose that this combination could be a rational treatment of choice in congenital hypotrichosis associated with syndromes such as ectodermal dysplasias. The efficacy and safety of long-term treatment needs to be explored further.
    Discuss this study in the Community →

    Research cited in this study

    6 / 6 results

    Related Community Posts Join

    6 / 1000+ results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Dutasteride Literally Saves Your Hair

      in Finasteride/Dutasteride  96 upvotes 6 months ago
      Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.

      community I was on 2.5 mg oral minoxidil

      in Progress Pictures  468 upvotes 5 months ago
      User took 2.5 mg oral minoxidil, saw hair growth but stopped due to excessive body hair. Recently started finasteride and plans to update progress.

      community Why does it seem everyone favors finasteride over dutasteride?

      in Female  62 upvotes 7 months ago
      The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.

    Related Research

    3 / 3 results