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    Did you mean Clouston Syndrome?
    GlossaryClouston Syndrome

    Clouston syndrome, also known as hidrotic ectodermal dysplasia, is a rare genetic disorder characterized by hair loss, nail abnormalities, and skin changes. It is caused by mutations in the GJB6 gene, which encodes a protein essential for the function of gap junctions in epithelial cells. Individuals with Clouston syndrome typically experience hair thinning or complete alopecia, often accompanied by the presence of thickened or ridged nails. This condition highlights the intricate relationship between genetic factors and hair biology, particularly in the development and maintenance of hair follicles.

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      community Day 1 of Combating Diffuse Thinning

      in Treatment  6 upvotes 2 years ago
      A user noticed worsening hair thinning and started using rosemary oil, jojoba oil, a 1.5mm dermastamp, 1% ketoconazole shampoo, scalp massages, and vitamin D tablets. They may switch to Minoxidil and Finasteride if needed.

      community Taking part in a Clascoterone Study

      in Treatment  6 upvotes 2 years ago
      The conversation is about a person considering participating in a study for Clascoterone, a topical cream for hair loss, and seeking advice on potential side effects. They have mild hair loss and are not currently using other treatments like finasteride.

      community Has anyone tried CB-01-03 aka Clascoterone?

      in Research/Science  2 upvotes 3 weeks ago
      Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.

      community Opinion on the recent clascoterone breakthrough?

      in Treatment  3 upvotes 2 months ago
      Clascoterone has shown promising results in increasing hair density without systemic side effects, potentially offering benefits similar to finasteride. There is skepticism due to the lack of published photos despite the market interest.