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    Glossary Complete Androgen Insensitivity Syndrome

    genetic condition causing male individuals to develop female traits

    Complete Androgen Insensitivity Syndrome (CAIS) is a genetic condition where an individual who is genetically male (with one X and one Y chromosome) is resistant to male hormones called androgens. As a result, the person has the physical traits of a female but does not have a uterus or ovaries, and typically has undescended testes. This condition is caused by mutations in the AR gene, which affects the body's ability to respond to androgens.

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    1. Female pattern hair loss in complete androgen insensitivity syndrome British Journal of Dermatology · 2010 · 54 citations
    2. A Novel Androgen Receptor Gene Mutation in a 46,XY Patient: Complete Androgen Insensitivity Syndrome AACE Clinical Case Reports · 2015 · 1 citations
    3. An adolescent girl presenting with primary amenorrhea: A case report of complete androgen insensitivity syndrome IJEM case reports · 2023
    4. A Case of Hair Regrowth in a Patient with Complete Androgen Insensitivity Syndrome and Female Pattern Hair Loss Journal of clinical and cosmetic dermatology · 2020
    5. Clinical, Hormonal, Behavioral, and Genetic Characteristics of Androgen Insensitivity Syndrome in a Brazilian Cohort: Five Novel Mutations in the Androgen Receptor Gene The Journal of Clinical Endocrinology & Metabolism · 2003 · 174 citations
    6. Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity. UNC Libraries · 2020 · 32 citations
    7. Identification of two additional novel mutations in the AR gene associated with severe forms of androgen insensitivity syndrome Steroids · 2019 · 1 citations
    8. SAT-213 Late Diagnosis of Complete Androgen Insensitivity Journal of the Endocrine Society · 2019
    9. Molecular genetics of androgen insensitivity Adolescent and pediatric gynecology · 1995
    10. Graham Little-Piccardi-Lassueur syndrome associated with androgen insensitivity syndrome (testicular feminization) Journal of The European Academy of Dermatology and Venereology · 2004 · 22 citations
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    Community 2 of 45

    1. Does DHT Cause Complete Baldness? Reddit · 27 Aug 2025
    2. AH-001 another topical AR degrader beside GT20029, completed Phase I Reddit · 13 Nov 2025
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