research Nevoid Basal Carcinoma Syndrome (Gorlin Syndrome) and Pronounced Androgenic Alopecia in a Woman with a Novel Mutation p.Leu1159fsx32 in the PTCH Gene
A woman with a new PTCH gene mutation has both Gorlin syndrome and severe hair loss.
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5 / 220 results research Novel Compound Heterozygous Variants in the CDC6 Gene in a Russian Patient with Meier-Gorlin Syndrome
A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.
research Anti-Basal Cell Carcinoma Efficacy of a Topical Hedgehog Inhibitor Without Adverse Effects in Gorlin Syndrome Patients in a Phase 2 Randomized Controlled Trial
Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.
research Experience with Sonidegib in Patients with Advanced Basal Cell Carcinoma: Case Reports
Sonidegib effectively treated advanced basal cell carcinoma with mild side effects.
research A Non-Cell Autonomous Dermal Hedgehog Signaling Mechanism for Follicular Neoplasia and Induction
Mutations in the SHH pathway in certain skin cells can cause skin tumors and abnormal hair growth.
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5 / 11 resultscommunity Try to find picture of Justin Bieber without a hat in the last two years - challenge impossible
The conversation discusses Justin Bieber's apparent hair loss and the public's reaction to it, with some speculating he's had a hair transplant or is avoiding hair loss medications due to side effects or medical conditions. There's also mention of his past comments on Prince William's balding and the irony of his current situation.
community Male pattern baldness, and mental health
A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.
community I accepted my hair loss and shaved it. Hair loss controls me no more
User accepted hair loss, shaved head, and feels free. Others joke about confusing photo angles.
community Pyrilutamide is literally my only hope
Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.
community 36m Is there any hope left? Fin hasn’t been working
The post discusses a user's struggle with hair loss and the ineffectiveness of finasteride. Suggestions from the conversation include trying oral minoxidil and considering a 3200 graft hair transplant.