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    Glossary KID Syndrome

    rare genetic disorder causing eye, skin, and hearing issues

    KID Syndrome, or Keratitis-Ichthyosis-Deafness Syndrome, is a rare genetic disorder characterized by three main features: eye problems (keratitis), skin abnormalities (ichthyosis), and hearing loss (deafness). It is typically caused by mutations in the GJB2 gene, which affects the protein connexin 26, crucial for cell communication in the skin and inner ear.

    Research 10 of 147

    1. A novel mutation in the connexin 26 gene (<i>GJB2</i>) in a child with clinical and histological features of keratitis–ichthyosis–deafness (KID) syndrome Clinical and Experimental Dermatology · 2010 · 34 citations
    2. Porokeratotic Eccrine Duct and Hair Follicle Nevus (PEHFN) Associated with Keratitis-Ichthyosis-Deafness (KID) Syndrome Pediatric dermatology · 2010 · 17 citations
    3. Sebaceous carcinoma arising at a chronic candidiasis skin lesion of a patient with keratitis-ichthyosis-deafness (KID) syndrome British Journal of Dermatology · 2011 · 6 citations
    4. KID Syndrome: Report of a Case and Support for Its Reclassification as an Ectodermal Dysplasia Pediatric Dermatology · 2000 · 6 citations
    5. Case Report of Wound Treatment with Hyiodine Gel in an Occasional KID Syndrome Patient Journal of Clinical Medicine · 2025
    6. Severe form of keratitis–ichthyosis–deafness (KID) syndrome associated with septic complications The Journal of Dermatology · 2010 · 29 citations
    7. A Novel Connexin 26 Mutation in a Patient Diagnosed with Keratitis–Ichthyosis–Deafness Syndrome 2002 · 152 citations
    8. Keratitis-Ichthyosis-Deafness Syndrome Caused by Missense Mutation in GJB2 Encoding Connexin 26 in a Chinese Patient International journal of dermatology and venereology · 2022
    9. Ichthyosiform Erythroderma, a Multifaceted Syndromic Entity Pediatrics in review · 2021
    10. 478 Mutation-specific siRNA Knockdown of GJB2 − Potential gene therapy for Keratitis-ichthyosis-deafness Syndrome Journal of Investigative Dermatology · 2017
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