Sebaceous Carcinoma Arising at a Chronic Candidiasis Skin Lesion of a Patient with Keratitis-Ichthyosis-Deafness (KID) Syndrome

    July 2011 in “ British Journal of Dermatology ”
    Yo Kaku, Hideaki Tanizaki, Miki Tanioka, Jun‐ichi Sakabe, Aya Miyagawa‐Hayashino, Y. Tokura, Yoshiki Miyachi, Kenji Kabashima
    Image of study
    TLDR A man with KID syndrome developed a rare cancer in a long-term skin infection.
    The document described a unique case of a 30-year-old Japanese man with keratitis-ichthyosis-deafness (KID) syndrome who developed sebaceous carcinoma within a chronic candidiasis skin lesion after over 10 years of treatment with oral fluconazole. The carcinoma, which appeared as a nodule on his left buttock at age 20 and later became erosive, was confirmed through histological examination. The patient exhibited typical KID syndrome symptoms and had a heterozygous genetic mutation linked to the condition. After switching to oral itraconazole therapy, there was a reduction in hyperkeratotic plaques. The case highlighted the need for careful malignancy screening in KID syndrome patients due to the unusual early onset and location of the sebaceous carcinoma.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 52 results

    Similar Research

    5 / 1000+ results
      Index

      research Index

      November 2019 in “Harper's Textbook of Pediatric Dermatology”
      The document is a detailed medical reference on skin and genetic disorders.
      Index

      research Index

      September 2019
      The document is a detailed guide on skin conditions and treatments for dermatologists.
      Atlas of Geriatric Dermatology

      research Atlas of Geriatric Dermatology

      2 citations, January 2014 in “Springer eBooks”
      The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.
      Hair and Nail Disorders of Childhood

      research Hair and Nail Disorders of Childhood

      7 citations, December 2008 in “Expert Review of Dermatology”
      The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.