TLDR Combination therapy improves hair growth in advanced hair loss.
This study was conducted to determine if a combination of topical minoxidil and tretinoin, along with oral finasteride, could be used as an effective treatment for Androgenetic Alopecia (AGA). A 32-year old man with advanced stage V AGA saw marked improvement after 3 months, with continued gradual improvement over the next 9 months. The combination therapy showed promise in improving cosmetic appearance, although further research is needed to understand the synergistic effects of the two treatments.
59 citations,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
13 citations,
October 1993 in “International Journal of Dermatology” Minoxidil effectively promotes hair regrowth in younger patients with small balding areas.
34 citations,
February 1992 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride and minoxidil together promote hair growth better than either alone.
30 citations,
April 1990 in “Clinical Pharmacology & Therapeutics” Tretinoin cream boosts minoxidil absorption, possibly improving hair loss treatment.
37 citations,
January 1987 in “Dermatology” Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.
73 citations,
October 1986 in “Journal of the American Academy of Dermatology” Tretinoin may help hair growth and works better when combined with minoxidil.
14 citations,
September 2003 in “Archives of Dermatology” Finasteride may not stop severe hair loss after stopping minoxidil.
72 citations,
January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
1 citations,
December 1995 in “Archives of Dermatology” The combination of topical minoxidil and oral finasteride improved hair regrowth in a man with advanced hair loss.