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Glossary Hair Shaft Disorders

conditions affecting hair structure, causing brittleness and breakage

Hair Shaft Disorders are conditions that affect the structure and integrity of the hair shaft, leading to issues like brittleness, breakage, and abnormal hair texture. These disorders can be genetic or acquired and often result from defects in the proteins that make up the hair, such as keratin, or from external factors like excessive heat or chemical treatments.

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Research

5 / 1000+ results

research Dermatoscopy of hair shaft disorders

68 citations , August 2012 in “Journal of the American Academy of Dermatology”

This paper discusses the use of dermatoscopy as a fast, noninvasive technique for diagnosing hair shaft disorders and reports no new results; the authors highlight its advantages over traditional microscopy methods.

research Trichoscopy in Hair Shaft Disorders

36 citations , August 2018 in “Dermatologic Clinics”

This article reviews various hair abnormalities observable through trichoscopy in conditions like monilethrix, trichorrhexis nodosa, and ectodermal dysplasias, with no new clinical findings reported.

research Hair shaft disorders in children – An update

12 citations , January 2023 in “Indian Dermatology Online Journal”

This review discusses the diagnostic and therapeutic challenges of hair shaft disorders and suggests diagnostic tools like trichoscopy and light microscopy, but reports no new clinical results.

research AN UPDATE OF HAIR SHAFT DISORDERS

12 citations , October 1996 in “Dermatologic clinics”

This review outlines the diagnostic criteria for congenital and hereditary hair shaft abnormalities and emphasizes the need to understand the weathering process in assessing these disorders.

System Support in the Formation and Growth of Hair in Alopecias and Hair Shaft Disorders

research System support in the forming and growth of hair in alopecias and the disorders of hair shaft

1 citations , January 2020 in “Дерматологія та венерологія”

Natubiotin is effective for treating different hair loss conditions when used with other therapies.

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Community Join

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community Hair loss research is a money grab

227 upvotes 10 months ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

140 upvotes 11 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 4 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community Ray Peat: Testosterone Isn’t the Culprit, Prolactin and Cortisol Drive Hair Loss (2016)

in Research/Science 110 upvotes 10 months ago

Prolactin and cortisol are identified as key factors in hair loss, with stress hormones impacting hair shedding. Finasteride and minoxidil are effective treatments, while DHT's role and individual sensitivity are significant factors.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Adenosine

nucleoside used for hair regrowth stimulant properties

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

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Clinics

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

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Hairo Fallas