Topical Minoxidil Treatment for Congenital Alopecia in Hypohidrotic Ectodermal Dysplasia

March 2013

Hae Young Lee, In-Kyu Chang, Myung Im, Young Joon Seo, Jeung-Hoon Lee, Young Ho Lee

topical minoxidil congenital alopecia hypohidrotic ectodermal dysplasia ectodermal derivatives Rogaine

Studysummary This report describes a case where a 4-year-old boy with congenital alopecia due to hypohidrotic ectodermal dysplasia experienced significant hair growth after using topical minoxidil.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

A decade ago, a case study was conducted on a 4-year-old boy with congenital alopecia caused by hypohidrotic ectodermal dysplasia, a rare genetic disorder characterized by the absence or dysgenesis of at least 2 ectodermal derivatives, such as hair, nails, teeth, or sweat glands. The boy showed dramatic hair growth after application of 3% topical minoxidil, 1 mL twice daily, for a year. The treatment had no adverse effects and improved the boy's quality of life. The study concluded that topical minoxidil alone can be used as the treatment of choice for congenital alopecia in ectodermal dysplasia.

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3 / 3 results

Alopecia in Congenital Hidrotic Ectodermal Dysplasia Responding to Treatment with a Combination of Topical Minoxidil and Tretinoin

research Alopecia in Congenital Hidrotic Ectodermal Dysplasia Responding to Treatment with a Combination of Topical Minoxidil and Tretinoin

20 citations , January 2009 in “International Journal of Dermatology”

This case report describes a patient with Clouston's syndrome and alopecia who responded positively to topical treatment with minoxidil and tretinoin.

research Optimal Management of Hair Loss (Alopecia) in Children

49 citations , January 2003 in “American Journal of Clinical Dermatology”

This review discusses various pediatric hair loss conditions and treatments, highlighting the importance of a holistic approach and noting that no single treatment is universally effective.

A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations , August 2002 in “Journal of The American Academy of Dermatology”

This study found that 5% topical minoxidil significantly increased hair regrowth and improved psychosocial perceptions of hair loss in men with androgenetic alopecia compared to 2% topical minoxidil and placebo over 48 weeks.