Current Treatment of Alopecia Areata

    Jerry Shapiro
    From the encyclopedia
    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Studysummary This review discusses various treatments for alopecia areata, highlighting their limitations and individualized approach, and reports no new clinical results.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The document discussed the treatment of Alopecia Areata (AA), noting the lack of FDA-approved treatments and the use of various options like steroids, topical immunotherapy, minoxidil, anthralin, and immunosuppressants, none of which were curative or preventive. Intralesional corticosteroids were first-line for adults with limited involvement, while topical treatments had varying efficacy. Topical sensitizers like DPCP and SADBE had 50-60% success rates but common relapses. Systemic treatments had high relapse rates and significant side effects. Support groups and patient education were emphasized. DPCP was preferred, with intralesional triamcinolone acetonide for partial responders, and alternative treatments like 5% minoxidil, topical clobetasol propionate, or anthralin were considered if DPCP failed. For eyebrow AA, minoxidil 5% with or without triamcinolone injections was suggested, and dermatography or medical tattooing for prolonged loss. Scalp prostheses were also valuable during or after treatment.
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