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GlossarySquaric Acid Dibutylester

chemical used in dermatology to treat alopecia areata

Squaric Acid Dibutylester (SADBE) is a chemical compound used in dermatology, particularly for treating alopecia areata, an autoimmune condition that causes hair loss. It works as a topical immunotherapy agent, inducing a mild allergic reaction that can help stimulate hair regrowth by modulating the immune response.

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research Childhood Epidermolysis Bullosa Acquisita During Squaric Acid Dibutyl Ester Immunotherapy for Alopecia Areata

12 citations , May 2016 in “British Journal of Dermatology”

A 6-year-old boy's skin condition improved after stopping a specific treatment and starting new medications.

research The Pattern and Profile of Alopecia Areata in Singapore: A Study of 219 Asians

275 citations , November 2002 in “International Journal of Dermatology”

Alopecia areata mainly affects young people and has significant psychological impacts, especially in males.

research The Therapeutic Use of Topical Contact Sensitizers in Benign Dermatoses

60 citations , September 2001 in “British journal of dermatology/British journal of dermatology, Supplement”

Topical contact sensitizers can treat certain skin conditions by changing the immune response.

research A Chronic Contact Eczema Impedes Migration of Antigen-Presenting Cells in Alopecia Areata

24 citations , May 2006 in “Journal of Investigative Dermatology”

Chronic contact eczema may help hair regrowth in alopecia areata by reducing certain immune cell movement.

research The Therapeutic Use of Topical Contact Sensitizers in Benign Dermatoses

23 citations , July 2008 in “British journal of dermatology/British journal of dermatology, Supplement”

Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.

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