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    Did you mean Squaric Acid Dibutylester?
    Glossary Squaric Acid Dibutylester

    chemical used in dermatology to treat alopecia areata

    Squaric Acid Dibutylester (SADBE) is a chemical compound used in dermatology, particularly for treating alopecia areata, an autoimmune condition that causes hair loss. It works as a topical immunotherapy agent, inducing a mild allergic reaction that can help stimulate hair regrowth by modulating the immune response.

    Research 10 of 336

    1. Childhood epidermolysis bullosa acquisita during squaric acid dibutyl ester immunotherapy for alopecia areata British Journal of Dermatology · 2016 · 12 citations
    2. 440 Squaric acid dibutylester, used in alopecia areata immunotherapy, promotes innate immune-driven hair growth with CD206+ macrophage accumulation in the dermis Journal of Investigative Dermatology · 2024
    3. Treatment of Alopecia Areata With Squaric Acid Dibutylester Archives of Dermatology · 1987 · 42 citations
    4. Treatment of alopecia areata with squaric acid dibutylester Clinics in dermatology · 2014 · 21 citations
    5. Discoid lupus erythematosus exacerbated by contact dermatitis caused by use of squaric acid dibutylester for topical immunotherapy in a patient with alopecia areata The Journal of Dermatology · 2008 · 15 citations
    6. Topical use of calcipotriol does not potentiate squaric acid dibutylester effectiveness in the treatment of alopecia areata Journal of Dermatological Treatment · 1995 · 5 citations
    7. Hapten‐induced lymphadenosis benigna cutis secondary to squaric acid dibutylester sensitization for alopecia areata The Journal of Dermatology · 2014 · 3 citations
    8. Severe pustular lesions induced by topical immunotherapy with squaric acid dibutylester for alopecia totalis Journal of Cutaneous Immunology and Allergy · 2019 · 1 citations
    9. Squaric Acid Dibutylester Promotes Innate Immune-Driven Hair Growth with CD206+ Macrophage Accumulation in the Dermis JID Innovations · 2025
    10. 965 The importance of CD206+ macrophages in squaric acid dibutylester-induced hair cycle activation Journal of Investigative Dermatology · 2023
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