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    Glossary Squaric Acid Dibutylester

    chemical used in dermatology to treat alopecia areata

    Squaric Acid Dibutylester (SADBE) is a chemical compound used in dermatology, particularly for treating alopecia areata, an autoimmune condition that causes hair loss. It works as a topical immunotherapy agent, inducing a mild allergic reaction that can help stimulate hair regrowth by modulating the immune response.

    Research 10 of 348

    1. Treatment of Alopecia Areata With Squaric Acid Dibutylester Archives of Dermatology · 1987 · 42 citations
    2. Treatment of alopecia areata with squaric acid dibutylester Clinics in dermatology · 2014 · 21 citations
    3. Discoid lupus erythematosus exacerbated by contact dermatitis caused by use of squaric acid dibutylester for topical immunotherapy in a patient with alopecia areata The Journal of Dermatology · 2008 · 15 citations
    4. Topical use of calcipotriol does not potentiate squaric acid dibutylester effectiveness in the treatment of alopecia areata Journal of Dermatological Treatment · 1995 · 5 citations
    5. Hapten‐induced lymphadenosis benigna cutis secondary to squaric acid dibutylester sensitization for alopecia areata The Journal of Dermatology · 2014 · 3 citations
    6. Severe pustular lesions induced by topical immunotherapy with squaric acid dibutylester for alopecia totalis Journal of Cutaneous Immunology and Allergy · 2019 · 1 citations
    7. Squaric Acid Dibutylester Promotes Innate Immune-Driven Hair Growth with CD206+ Macrophage Accumulation in the Dermis JID Innovations · 2025
    8. 965 The importance of CD206+ macrophages in squaric acid dibutylester-induced hair cycle activation Journal of Investigative Dermatology · 2023
    9. 440 Squaric acid dibutylester, used in alopecia areata immunotherapy, promotes innate immune-driven hair growth with CD206+ macrophage accumulation in the dermis Journal of Investigative Dermatology · 2024
    10. Childhood epidermolysis bullosa acquisita during squaric acid dibutyl ester immunotherapy for alopecia areata British Journal of Dermatology · 2016 · 12 citations
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