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GlossarySquaric Acid Dibutylester

chemical used in dermatology to treat alopecia areata

Squaric Acid Dibutylester (SADBE) is a chemical compound used in dermatology, particularly for treating alopecia areata, an autoimmune condition that causes hair loss. It works as a topical immunotherapy agent, inducing a mild allergic reaction that can help stimulate hair regrowth by modulating the immune response.

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research Treatment of Alopecia Areata With Squaric Acid Dibutylester

42 citations, August 1987 in “Archives of Dermatology”

Squaric acid dibutylester led to complete hair regrowth in 28.5% of patients with alopecia areata.

research Treatment of Alopecia Areata with Squaric Acid Dibutylester

21 citations, December 2014 in “Clinics in dermatology”

Squaric acid dibutylester effectively treats alopecia areata.

research Discoid Lupus Erythematosus Exacerbated by Contact Dermatitis Caused by Use of Squaric Acid Dibutylester for Topical Immunotherapy in a Patient with Alopecia Areata

15 citations, March 2008 in “The Journal of Dermatology”

Topical squaric acid dibutylester worsened discoid lupus erythematosus in a patient.

research Topical Use of Calcipotriol Does Not Potentiate Squaric Acid Dibutylester Effectiveness in the Treatment of Alopecia Areata

5 citations, January 1995 in “Journal of Dermatological Treatment”

Calcipotriol does not improve the effectiveness of squaric acid dibutylester in treating alopecia areata.

research Hapten-Induced Lymphadenosis Benigna Cutis Secondary to Squaric Acid Dibutylester Sensitization for Alopecia Areata

3 citations, January 2014 in “The Journal of Dermatology”

Squaric acid dibutylester for alopecia areata can cause benign skin lymphoid growths.

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