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    Glossary Squaric Acid Dibutylester

    chemical used in dermatology to treat alopecia areata

    Squaric Acid Dibutylester (SADBE) is a chemical compound used in dermatology, particularly for treating alopecia areata, an autoimmune condition that causes hair loss. It works as a topical immunotherapy agent, inducing a mild allergic reaction that can help stimulate hair regrowth by modulating the immune response.

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    1. Treatment of Alopecia Areata With Squaric Acid Dibutylester Archives of Dermatology · 1987 · 42 citations
    2. Treatment of alopecia areata with squaric acid dibutylester Clinics in dermatology · 2014 · 21 citations
    3. Discoid lupus erythematosus exacerbated by contact dermatitis caused by use of squaric acid dibutylester for topical immunotherapy in a patient with alopecia areata The Journal of Dermatology · 2008 · 15 citations
    4. Topical use of calcipotriol does not potentiate squaric acid dibutylester effectiveness in the treatment of alopecia areata Journal of Dermatological Treatment · 1995 · 5 citations
    5. Hapten‐induced lymphadenosis benigna cutis secondary to squaric acid dibutylester sensitization for alopecia areata The Journal of Dermatology · 2014 · 3 citations
    6. Severe pustular lesions induced by topical immunotherapy with squaric acid dibutylester for alopecia totalis Journal of Cutaneous Immunology and Allergy · 2019 · 1 citations
    7. Squaric Acid Dibutylester Promotes Innate Immune-Driven Hair Growth with CD206+ Macrophage Accumulation in the Dermis JID Innovations · 2025
    8. 965 The importance of CD206+ macrophages in squaric acid dibutylester-induced hair cycle activation Journal of Investigative Dermatology · 2023
    9. 440 Squaric acid dibutylester, used in alopecia areata immunotherapy, promotes innate immune-driven hair growth with CD206+ macrophage accumulation in the dermis Journal of Investigative Dermatology · 2024
    10. Childhood epidermolysis bullosa acquisita during squaric acid dibutyl ester immunotherapy for alopecia areata British Journal of Dermatology · 2016 · 12 citations
    11. Angioedema After Squaric Acid Treatment in a 6‐Year‐Old Girl Pediatric Dermatology · 2016 · 6 citations
    12. Efficacy of topical sensitizers in the treatment of alopecia areata Journal of the American Academy of Dermatology · 1998 · 132 citations
    13. Alopecia Areata: Treatment of Today and Tomorrow Journal of Investigative Dermatology Symposium Proceedings · 2003 · 48 citations
    14. Topical immunotherapy in alopecia areata International journal of trichology · 2010 · 45 citations
    15. Review of treatment for alopecia totalis and alopecia universalis International Journal of Dermatology · 2017 · 44 citations
    16. Current and Potential Agents for the Treatment of Alopecia Areata> Current pharmaceutical design · 2001 · 41 citations
    17. Alopecia areata: revisão e atualização Anais Brasileiros de Dermatologia · 2005 · 39 citations
    18. A Chronic Contact Eczema Impedes Migration of Antigen-Presenting Cells in Alopecia Areata Journal of Investigative Dermatology · 2006 · 24 citations
    19. Chronic delayed-type hypersensitivity reaction as a means to treat alopecia areata Clinical & Experimental Immunology · 2004 · 20 citations
    20. Renbök Phenomenon and Contact Sensitization in a Patient With Alopecia Universalis Archives of Dermatology · 2010 · 18 citations
    21. Treatment of Alopecia Areata With Topical Sensitizers Dermatitis · 2015 · 15 citations
    22. Alopecia Areata International Journal of Dermatology · 1985 · 14 citations
    23. Childhood alopecia areata: What treatment works best? MOspace Institutional Repository (University of Missouri) · 2011 · 1 citations
    24. Combination use of triamcinolone acetonide and immunotherapy as a new therapeutic option in alopecia totalis Trends in Immunotherapy · 2020
    25. Lasers for Other Specific Dermatologic Disorders 2019
    26. Alopecia areata: Treatment options DOAJ (DOAJ: Directory of Open Access Journals) · 2006
    27. 13. Wound Healing & Hair Journal of Cutaneous Medicine and Surgery · 2003
    28. Use of Contact Immunotherapy in the Treatment of Skin Diseases Other than Alopecia Areata Dermatology and therapy · 2022
    29. The Effect of Drugs on Hair Handbook of experimental pharmacology · 1989
    30. The pattern and profile of alopecia areata in Singapore – a study of 219 Asians International Journal of Dermatology · 2002 · 275 citations