TLDR Psoriasis or contact dermatitis can override alopecia areata, allowing hair growth.
The document described a patient with concurrent psoriasis and alopecia universalis, where psoriasis plaques on his extremities showed normal hair growth, the only such growth on his body. Biopsies confirmed plaque psoriasis with normal hair follicles and alopecia universalis with a peribulbar lymphocytic infiltrate. The patient's psoriatic plaques cleared with narrow-band UV-B phototherapy, but hair growth was maintained. His scalp alopecia responded to squaric acid dibutylester contact sensitization therapy. This case illustrated how different immune responses can interact, with psoriasis or contact dermatitis taking precedence over alopecia areata, possibly due to cytokine cross-regulation.
69 citations,
February 2008 in “The American journal of pathology” Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
286 citations,
August 2007 in “Journal of Clinical Investigation” Alopecia areata is an autoimmune disease where T cells attack hair follicles.
48 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Contact sensitizers like DCP and SADBE are the most effective treatments for alopecia areata.
37 citations,
January 2003 in “Journal of the European Academy of Dermatology and Venereology” Turner's syndrome may be linked to autoimmune diseases like psoriasis and alopecia areata, needing comprehensive care.
1 citations,
August 2023 in “Acta dermato-venereologica” Corticosteroids are the most common treatment for alopecia areata, but many patients need better options.
6 citations,
November 2022 in “Journal of autoimmunity” JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
October 2022 in “Journal of Armed Forces Medical College, Bangladesh” Tofacitinib is effective and safe for treating alopecia areata.
39 citations,
April 2016 in “Case Reports in Dermatology” Tofacitinib temporarily regrew hair in a man with alopecia, but its effects didn't last.
5 citations,
June 2015 in “Veterinary dermatology” A dog with complete hair loss regrew most hair after treatment, with no relapse after stopping treatment.
39 citations,
April 2003 in “Australasian journal of dermatology” PUVA treatment led to significant hair regrowth in over half of the patients with alopecia areata totalis and universalis.
