Hapten-Induced Lymphadenosis Benigna Cutis Secondary to Squaric Acid Dibutylester Sensitization for Alopecia Areata

The letter to the editor discussed a case of hapten-induced lymphadenosis benigna cutis as a secondary effect of sensitization to squaric acid dibutylester (SADBE) used in the treatment of alopecia areata. The authors from the Department of Dermatology at Keio University School of Medicine in Tokyo, Japan, highlighted the occurrence of this benign lymphoid hyperplasia following the topical application of SADBE, a common sensitizing agent for alopecia areata. The letter emphasized the need for awareness of such potential side effects in clinical practice.