Angioedema After Squaric Acid Treatment in a 6-Year-Old Girl

October 2016 in “ Pediatric Dermatology ”

Chen Chen, Valerie M. Carlberg, Daniela Kroshinsky

alopecia areata angioedema squaric acid dibutylester topical sensitizer hair regrowth AA SADBE

TLDR A 6-year-old girl had a rare allergic reaction to a hair regrowth treatment.

A 6-year-old girl with alopecia areata (AA) developed angioedema after treatment with squaric acid dibutylester (SADBE), a topical sensitizer commonly used for AA due to its low side-effect profile and potential for hair regrowth. This case highlighted a rare adverse reaction to SADBE, emphasizing the need for awareness and monitoring of potential side effects in pediatric patients undergoing this treatment.

View this study on doi.org →

Discuss this study in the Community →

Research cited in this study

3 / 3 results

research Treatment of Alopecia Areata with Squaric Acid Dibutylester

21 citations, December 2014 in “Clinics in dermatology”

Squaric acid dibutylester effectively treats alopecia areata.

research Extensive Scalp Angioedema Following High-Dose Diphenylcyclopropenone for Alopecia Areata

5 citations, January 2014 in “Hospital pharmacy”

Using a strong allergy medicine too often on the scalp can cause swelling and inflammation.

research Autoimmunity: Alopecia Areata

143 citations, January 2004 in “Journal of Investigative Dermatology Symposium Proceedings”

Alopecia areata is an autoimmune disease causing hair loss, treatable with immune-modulating drugs, and linked to genetics.

Related Community Posts Join

6 / 1000+ results

community Alopecia Areata Question

in Treatment 2 upvotes 3 years ago

A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

community mbp alopecia areata or vitamin deficiency

in Chat 5 months ago

A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

community Olumiant alternative for Alopecia Areata?

in Treatment 1 upvotes 1 year ago

A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

community Covid (likely) induced alopecia areata - now 2nd round of Covid, what can I expect?

in Treatment 1 upvotes 1 year ago

After experiencing hair loss due to alopecia areata following COVID-19 vaccination and infection, the individual saw improvement with steroid treatments and Olumiant. They paused Olumiant during a second COVID-19 infection and expressed concern about potential hair loss flare-ups.

community Onion Juice - An effective topical treatment for Alopecia Areata 🧬

in Treatment 1 year ago

Onion juice, when applied topically, is an effective treatment for Alopecia Areata, showing significant hair regrowth in both males and females. The study suggests it could be interesting to test its effectiveness on Androgenic Alopecia.

community Nearly 40% of Adults with Alopecia Areata Taking OLUMIANT® 4-mg Saw at Least 80% Scalp Hair Coverage at 52 Weeks

in Research/Science 6 upvotes 2 years ago

Nearly 40% of adults with alopecia areata achieved at least 80% scalp hair coverage after 52 weeks of taking OLUMIANT® 4-mg. The conversation distinguishes this success from androgenetic alopecia, which is a different type of hair loss.

Related Research

2 / 2 results

research Baricitinib Results in Eyebrow and Eyelash Growth in Patients With Alopecia Areata Who Do Not Achieve 20% or Less Scalp Hair Loss

1 citations, September 2022 in “Journal of The American Academy of Dermatology”

Baricitinib helps grow eyebrows and eyelashes in severe alopecia areata patients.

research Adverse Systemic Reaction to Dinitrochlorobenzene

14 citations, June 1982 in “Archives of Dermatology”

A man had bad reactions to a hair loss treatment called DNCB.