TLDR Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.
Topical contact sensitizers like dinitrochlorobenzene, squaric acid dibutyl ester, and diphencyprone have been used since the 1960s to treat alopecia areata and viral warts by altering the immune response. This systematic review examined the different sensitizers, treatment methods, factors affecting efficacy, and potential adverse effects. Despite their use, few dermatology departments in the U.K. offered this treatment.
Cited in this study
3 / 3 results
41 citations
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November 1993 in “Journal of The American Academy of Dermatology” DPCP helps treat severe hair loss, but 5% minoxidil doesn't add benefits.
36 citations
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March 1989 in “British journal of dermatology/British journal of dermatology, Supplement” DPCP is more effective than tretinoin gel for treating severe alopecia.
122 citations
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November 1984 in “Journal of the American Academy of Dermatology” No single treatment is consistently effective for alopecia areata, and more research is needed.
5 citations
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January 2022 in “Dermatology Reports” Tofacitinib treatment for hair loss may worsen acne.
October 2021 in “Dermatology Reports” Tofacitinib, a hair regrowth treatment, may worsen acne.
April 2019 in “International journal of research in dermatology” A child with rough nails also had hair loss and allergies.
37 citations
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October 2017 in “Clinical and Experimental Dermatology” Oral tofacitinib shows promise in treating atopic dermatitis and alopecia areata, but only slight improvement in vitiligo.
