Treatment of Chronic Severe Alopecia Areata with Topical Diphenylcyclopropenone and 5% Minoxidil: A Clinical and Immunopathologic Evaluation

    Jerry Shapiro, Jerry Tan, Vincent T. Ho … Victor Tron
    Studysummary This study found that DPCP treatment led to cosmetically acceptable hair regrowth in 38% of patients with chronic severe alopecia areata, while adding 5% minoxidil showed no significant clinical benefit.
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    Research cited in this study 9

    1. Treatment-Resistant Alopecia Areata: Combination Therapy with Minoxidil and Anthralin Archives of dermatology · 1990
    2. Allergic and Irritant Contact Dermatitis Compared in the Treatment of Alopecia Totalis and Universalis: A Comparison of the Value of Topical Diphencyprone and Tretinoin Gel British journal of dermatology/British journal of dermatology, Supplement · 1989
    3. Extensive Alopecia Areata: Results of Treatment with 3% Topical Minoxidil Cleveland Clinic Journal of Medicine · 1989
    4. Topical Minoxidil Solution (1% and 5%) in the Treatment of Alopecia Areata Journal of The American Academy of Dermatology · 1987
    5. Double-Blind, Placebo-Controlled Evaluation of Topical Minoxidil in Extensive Alopecia Areata Journal of The American Academy of Dermatology · 1987
    6. Topical Minoxidil (3%) in Extensive Alopecia Areata, Including Long-Term Efficacy Journal of The American Academy of Dermatology · 1987
    7. Immunohistochemical Characterization of the Cellular Infiltrate in Severe Alopecia Areata Before and After Minoxidil Treatment Dermatology · 1987
    8. Topical Minoxidil in Extensive Alopecia Areata, Including 3-Year Follow-Up Dermatology · 1987
    9. Topical Minoxidil Dose-Response Effect in Alopecia Areata Archives of Dermatology · 1986

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