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GlossaryIntercellular Adhesion Molecule 1 (ICAM-1)

protein aiding white blood cells in adhering to vessel walls

Intercellular Adhesion Molecule 1 (ICAM-1), also known as CD54, is a protein found on the surface of cells that plays a crucial role in the immune response. It helps white blood cells stick to and move through the walls of blood vessels to reach sites of infection or injury. This molecule is important in inflammation and can be involved in various diseases, including autoimmune disorders and cancer.

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research Intercellular Adhesion Molecule-1 and Hair Follicle Regression

29 citations , April 2000 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

ICAM-1 helps regulate hair growth cycles and skin remodeling.

research Oral Contraceptive Pill Treatment Alters Gene Expression of Inflammatory Markers in Polycystic Ovary Syndrome Women

2 citations , February 2023 in “BMC women's health”

Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.

research Polycystic Ovary Syndrome (PCOS): An Inflammatory, Systemic, Lifestyle Endocrinopathy

317 citations , April 2018 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Analysis of Gene Expression in Isolated Single Hair Follicles Using Semiquantitative Reverse-Transcriptase Polymerase Chain Reaction

research Analysis of Gene Expression in Isolated Single Hair Follicles Using Semiquantitative Reverse-Transcriptase Polymerase Chain Reaction

May 1995 in “Journal of Investigative Dermatology”

Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.

Management of Chemotherapy-Induced Alopecia Using a Topical Botanical Lotion via a Proposed Triple-Action on Apoptosis, Inflammation, and Collagen

research Management of Chemotherapy-Induced Alopecia Using a Topical Botanical Lotion via a Proposed Triple-Action on Apoptosis, Inflammation, and Collagen

July 2016 in “Cancer Research”

A topical lotion helped manage hair loss from chemotherapy by affecting cell death, inflammation, and collagen, with no side effects.

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community Fin bad responder? My experience

in Finasteride/Dutasteride 3 upvotes 4 years ago

The user experienced side effects from ecklonia cava similar to those reported with finasteride, including depression, brain fog, anxiety, and testicular pain. Despite these issues, the user is still considering using topical finasteride in the future.

community How the hell am I still losing hair

in Finasteride/Dutasteride 8 upvotes 5 months ago

The user has been experiencing sudden and aggressive hair shedding despite using oral dutasteride and topical minoxidil for six years, and recently added topical finasteride without improvement. Possible causes discussed include stress-related hair loss, dietary changes, or high DHT sensitivity, with suggestions to consult a doctor and consider adjusting treatments.

community If Ru58841 was an FDA approved medication and known to be safe would you recommend it before finasteride?

in Product 7 upvotes 2 years ago

The conversation discusses whether RU58841, if FDA approved and safe, would be recommended over finasteride for hair loss. Specific treatments mentioned include RU58841, finasteride, and minoxidil.

community Uncle not on meds vs. uncle on finasteride

in Progress Pictures 342 upvotes 7 months ago

A 43-year-old uncle on finasteride for 5 years has more hair than his 53-year-old uncle not on medication. Users discuss the effects and side effects of finasteride, including potential sexual side effects and gynecomastia.