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a topical anti-androgen with less systemic involvement
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5 / 21 resultslearn Spironolactone
powerful topical and oral anti-androgen used mostly by women
learn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
learn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
learn Melatonin
hormone commonly taken for sleep aid has some topical benefits for hair
Research
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research Treatment of Chronic Severe Alopecia Areata with Topical Diphenylcyclopropenone and 5% Minoxidil: A Clinical and Immunopathologic Evaluation
DPCP helps treat severe hair loss, but 5% minoxidil doesn't add benefits.
research Topical Immunotherapy of Severe Alopecia Areata with Diphenylcyclopropenone: Experience in an Iranian Population
DPCP is effective for treating severe alopecia areata, but relapse is common.
research Systematic Review and Quality Analysis of Studies on the Efficacy of Topical Diphenylcyclopropenone Treatment for Alopecia Areata
Topical DPCP is somewhat effective for hair loss in alopecia areata, but more research is needed.
research Comparative Trial on Efficacy of Topical Contact Immunotherapy with Dinitrochlorobenzene and Diphenylcyclopropenone in Alopecia Areata
Diphenylcyclopropenone is more effective and has fewer side effects than dinitrochlorobenzene for treating alopecia areata.
research Efficacy of Topical Diphenylcyclopropenone Maintenance Treatment for Patients with Alopecia Areata: A Retrospective Study
Diphenylcyclopropenone treatment helps prevent hair loss relapse in alopecia areata patients.
Community Join
5 / 1000+ resultscommunity Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride
Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.
community How effective is topical spironolactone for androgenic alopecia?
Topical spironolactone is discussed as a potential treatment for androgenic alopecia, with the user seeking feedback on its effectiveness. Minoxidil, finasteride, and other treatments like microneedling and keto shampoo are mentioned as alternatives.
community Topical fin 0.025%, min 5% - 2,5 months progress
The user started using topical finasteride 0.025% and minoxidil 5% twice daily, seeing initial improvement but later experiencing shedding and scalp pain. They are considering increasing the finasteride dose to 0.05% while using keto shampoo and dermarolling, and are debating the effectiveness of low versus standard doses of finasteride.
community Topical Metformin for Hair Transplant donor area skin/hair regeneration?
Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.
community Topical Minoxidil 5% , Microneedling 1.25mm and Saw palmetto
A 21-year-old male shares progress pictures showing improvement in hair growth using daily topical minoxidil 5%, microneedling 1.25mm, and 500mg of saw palmetto. He reports new and healthy hair growth, indicating success in managing androgenic alopecia.