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Did you mean Diphenylcyclopropenone?

GlossaryDiphenylcyclopropenone

topical immunotherapy agent used to treat alopecia areata

Diphenylcyclopropenone (DPCP) is a topical immunotherapy agent used primarily to treat alopecia areata, a condition that causes hair loss. It works by inducing a mild allergic reaction on the scalp, which is thought to distract the immune system from attacking hair follicles, thereby promoting hair regrowth.

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community Topical fin 0.025%, min 5% - 2,5 months progress

in Finasteride/Dutasteride 9 upvotes 1 week ago

The user started using topical finasteride 0.025% and minoxidil 5% twice daily, seeing initial improvement but later experiencing shedding and scalp pain. They are considering increasing the finasteride dose to 0.05% while using keto shampoo and dermarolling, and are debating the effectiveness of low versus standard doses of finasteride.

community Topical Metformin for Hair Transplant donor area skin/hair regeneration?

in Research/Science 3 upvotes 1 week ago

Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.

community Topical Minoxidil 5% , Microneedling 1.25mm and Saw palmetto

in Journals / Progress Pictures 47 upvotes 1 week ago

A 21-year-old male shares progress pictures showing improvement in hair growth using daily topical minoxidil 5%, microneedling 1.25mm, and 500mg of saw palmetto. He reports new and healthy hair growth, indicating success in managing androgenic alopecia.

community Topical - Dosage help (0.3% FIN per mL?)

in Finasteride/Dutasteride 1 upvotes 1 week ago

The user is considering starting a topical treatment for hair loss, using a spray containing 0.3% finasteride, 5% minoxidil, and 0.01% tretinoin. They are questioning the dosage and considering reducing the application to achieve 0.15% finasteride and 5% minoxidil.

community How long does topical fin reduce scalp DHT?

in Finasteride/Dutasteride 8 upvotes 2 weeks ago

Topical finasteride reduces scalp DHT effectively, with a suggested application of 1.5ml of 0.03% daily. It binds to scalp enzymes, potentially requiring daily or every other day application for sustained results.

community M18 - 7 Months on topical fin + min Not working for me

in Finasteride/Dutasteride 92 upvotes 1 month ago

Topical finasteride and minoxidil are not effective for the user, who is considering switching to oral treatments like finasteride or dutasteride. Many suggest oral medications are more effective, and some recommend additional treatments like microneedling and other topical solutions.

community Topical bimatoprost or latanoprost

in Product 10 upvotes 1 month ago

OP is considering adding topical bimatoprost or latanoprost to their hair loss treatment, which already includes oral minoxidil, and is seeking reliable sources for these products. Users discuss the effectiveness and sourcing of these treatments, with some using bimatoprost for both hairline and eyelashes, and others planning to use latanoprost mixed with finasteride.

community Topical latanoprost chance of eye color change?

in Product 1 upvotes 1 month ago

The user is using oral minoxidil for hair growth and is considering adding topical latanoprost, but is concerned about potential eye color change. They are seeking advice on the effectiveness of latanoprost for hair thickening and the risk of eye color change.

community Better Than Minoxidil? Topical Sodium Valproate

in Research/Science 51 upvotes 1 month ago

Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

community Topical minoxidil brand (and form of application) matters. You can be a hyper-responder to one product and a non-responder to another.

in Minoxidil 15 upvotes 1 month ago

Different minoxidil formulations affect hair growth and side effects. Higher propylene glycol and pH levels improve effectiveness but can cause scalp irritation.

community I promise it works. Topical minox + finasteride

in Update 1705 upvotes 1 month ago

Topical minoxidil and oral finasteride can effectively improve hair growth and slow hair loss, though results may vary. Consistency is important for achieving significant improvement.

community Topical Finasteride concetrations and amount applied

in Treatment 10 upvotes 1 month ago

Topical finasteride concentrations and application amounts are debated, with concerns that mainstream solutions may use arbitrary concentrations. A 0.25% solution with a specific application method is suggested as more appropriate than higher concentrations.

community Topical Min Progress Oct 2024 - Feb 2025

in Progress Pictures 276 upvotes 1 month ago

The user experienced hair growth using 5% topical Minoxidil foam twice daily from October 2024 to February 2025, without using finasteride due to family history of side effects. The user is considering other treatments like topical finasteride and received positive feedback on their progress.

community What happened to topical dutasteride??

in Finasteride/Dutasteride 28 upvotes 2 months ago

Topical dutasteride is considered for hair loss, but concerns about systemic absorption and side effects like reduced libido are common. Users have mixed results, with some preferring oral finasteride or dutasteride despite side effects, while others find topical treatments beneficial but challenging.

community Topical fin/min + microneedling 3 month results

in Progress Pictures 35 upvotes 2 months ago

The conversation discusses hair loss treatments, specifically using topical finasteride and minoxidil combined with microneedling, along with supplements like collagen, vitamin C/D, and saw palmetto. The user also mentions using a DHT-blocking shampoo and experimenting with cold showers and contrast therapy for hair health.

community How come topical fin doesn't deliver superior results when it suppresses scalp DHT more effectively than oral?

in Finasteride/Dutasteride 36 upvotes 2 months ago

Topical finasteride is believed to reduce scalp DHT more than oral forms, but its effectiveness is questioned due to inconsistent application and absorption. Oral finasteride is considered more effective because it consistently reduces systemic DHT, ensuring more reliable results.

community Is there any role for topical DHT antagonists, or does a 5-AR inhibitor remove the need for them as therapy

in Research/Science 2 upvotes 2 months ago

Topical androgen receptor antagonists may not be necessary if 5-AR inhibitors like finasteride or dutasteride effectively reduce DHT levels. Combining a 5-AR inhibitor with a topical androgen antagonist could potentially enhance treatment, but oral use of androgen antagonists is too risky due to severe side effects.

community topical Minoxidil - Ru58841 makes my hair look and feel really brittle and thin

in Minoxidil 1 upvotes 3 months ago

Topical Minoxidil and RU58841 can make hair look brittle and thin, possibly due to the propylene glycol in their solutions. Some users experience side effects like heart palpitations with RU58841, while others have no issues.

community Haircafe - TOPICAL minoxidil is an anti aging drug

in Minoxidil 245 upvotes 3 months ago

Topical minoxidil may cause skin aging effects like wrinkles and dark circles, possibly due to its alcohol content, while oral finasteride is reported to make users look younger. Switching to oral minoxidil or using moisturizers might help reduce these skin issues.

community Topical aldactone for men’s hair and muscle effects

in Treatments 18 upvotes 3 months ago

Topical aldactone is discussed for its effects on men's hair and muscles. The conversation explores its potential benefits and side effects compared to other treatments like Minoxidil, finasteride, and RU58841.

community Topical FIN/MIN 0.03% / 6% (Day 2) HAIR IS CURRENTLY WET & PARTED. As you can see my main issues are the crown / mid scalp area. Can’t wait until I start seeing results!

in Finasteride/Dutasteride 10 upvotes 3 months ago

The conversation discusses using topical finasteride and minoxidil for hair loss, focusing on the crown and mid-scalp areas. The user is optimistic about seeing results in 3 to 6 months.

community Topical fin formulation question

in Finasteride 91 upvotes 3 months ago

A user is making a homemade topical finasteride solution by dissolving crushed finasteride tablets in ethanol and PG. They are unsure if the final solution maintains the intended concentration after filtering and are considering adding more ethanol to ensure accuracy.

community Topical finasteride carrier/vehicle

in Finasteride 135 upvotes 4 months ago

The user is considering making a homemade topical finasteride solution using an ethanol-based carrier. They are inquiring if a solution containing partially denatured ethyl alcohol and benzalkonium chloride is suitable.

community Why not use hair system instead of Topical Hassle

in Hair Systems 18 upvotes 4 months ago

Topical treatments like minoxidil and finasteride are preferred for hair loss due to ease of use and natural appearance. Hair systems are considered high-maintenance and less genuine.

community 4 months topical minoxidil + 2 months finasteride

in Minoxidil 132 upvotes 4 months ago

Topical minoxidil and oral finasteride are effectively promoting hair growth with minimal side effects, such as no impact on sex drive. Users report positive results and reduced hair shedding, with some using a combination of topical foam containing both minoxidil and finasteride.

community Topical Minoxidil Hyperresponder

in Minoxidil 9 upvotes 5 months ago

Minoxidil helped regrow hair from NW3 to NW2 in 5 months despite initial shedding, with additional use of Vitamin D3/K2 on the scalp. Users discuss patience during shedding and the importance of continuing treatments like Minoxidil and Finasteride.

community Topical dutasteride valid success stories

in Finasteride/Dutasteride 1 upvotes 5 months ago

Topical dutasteride may not significantly reduce hair loss and could potentially increase testosterone, leading to further hair loss. Users report side effects like mood changes, sleep issues, and severe side effects, with no significant progress in hair regrowth.

community Topical Anti-Androgen users. What are y’all using currently? And what do you believe has the best chance of being approved? Or best results?

in Technology 13 upvotes 5 months ago

RU58841 is considered effective by some users, but finasteride and minoxidil are commonly used with varying dosages to manage side effects. Users report different experiences with treatments like pyrilutamide, fluridil, and RU58841, with some seeing results and others not.

community Topical Exosomes w derma roller??

in Research/Science 1 upvotes 6 months ago

The conversation discusses using topical exosomes with a derma roller for hair loss. Users also mention minoxidil for treatment.

community Topical min/fin for 8 months. Still seeing continuous miniaturisation

in General 50 upvotes 6 months ago

After 8 months of using topical finasteride, hair miniaturization continues, raising concerns about its effectiveness. Microneedling is suggested as a possible complementary treatment.