Vitiligo After Diphencyprone for Alopecia Areata

    January 2010 in “ Dermatology Research and Practice ”
    Mário Cézar Pires, João Mauricio Martins, Federico Montealegre, F Gatti
    TLDR DPCP treatment for alopecia areata can sometimes cause vitiligo.
    Diphencyprone (DPCP) has been used since the 1970s to treat alopecia areata and recalcitrant warts by altering the immune response. While generally effective and safe, DPCP can cause side effects such as local eczema, regional lymphadenopathy, and contact urticaria. Rarely, it can lead to more severe reactions like erythema multiforme-like reactions, hyperpigmentation, hypopigmentation, and vitiligo. This report detailed a case of a 30-year-old Brazilian male who developed vitiligo lesions after undergoing DPCP therapy for alopecia areata.
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