TLDR DPCP treatment for alopecia areata can sometimes cause vitiligo.
The document reported a case of a 30-year-old Brazilian male who developed vitiligo after undergoing diphencyprone (DPCP) therapy for alopecia areata. DPCP, a contact sensitizer used since the 1970s, has been effective in treating alopecia areata but can cause side effects, including rare cases of vitiligo. The patient experienced complete hair regrowth but developed hypopigmented lesions, which were confirmed to be vitiligo through a patch test. The study highlighted the need to inform patients about the potential risk of vitiligo, especially those with a personal or familial history of the condition.
47 citations,
September 1995 in “British Journal of Dermatology” Diphencyprone therapy for hair loss can cause vitiligo.
55 citations,
January 1988 in “Dermatology” Diphencyprone treatment for alopecia areata can cause vitiligo in some patients.
23 citations,
July 2008 in “British journal of dermatology/British journal of dermatology, Supplement” Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.
41 citations,
November 1993 in “Journal of The American Academy of Dermatology” DPCP helps treat severe hair loss, but 5% minoxidil doesn't add benefits.
29 citations,
August 2008 in “Current Opinion in Pediatrics” Hair loss in teenagers is hard to treat and lacks a cure, with some treatments available depending on the type of hair loss.
196 citations,
June 2008 in “International Journal of Dermatology” Dermoscopy helps diagnose and manage alopecia areata by showing specific hair changes.
