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Glossary Hypopigmentation

reduced melanin causes lighter skin patches

Hypopigmentation refers to a condition where patches of skin become lighter than the surrounding area due to a reduction in melanin, the pigment responsible for skin color. This can result from various causes, including skin injuries, certain medical conditions like vitiligo, or inflammatory skin disorders.

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learn Scalp Micropigmentation

scalp tattoos to mimic the appearance of light stubble

Why can't I see my scalp micropigmentation after a week? Initial fading of scalp micropigmentation is normal and density improves with subsequent sessions.
What pigments are used in scalp micropigmentation? Providers describe SMP pigments as organic, vegan and formulated for the scalp, but these are supplier and marketing descriptions rather than verified specifications, and clinics contradict each other on colour change and chemical content.
Does scalp micropigmentation cause hair loss? Scalp micropigmentation does not cause hair loss and is a cosmetic treatment.

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Research

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research Tyrosinase inhibition due to interaction of homocyst(e)ine with copper: the mechanism for reversible hypopigmentation in homocystinuria due to cystathionine beta-synthase deficiency.

74 citations , July 1995 in “PubMed”

This study suggests that reversible hypopigmentation in homocystinuric patients may result from tyrosinase inhibition by homocyst(e)ine, with in-vitro experiments showing copper sulfate reversing this inhibition.

research Decrypting the Potential of Nanotechnology-Based Approaches as Cutting-Edge for Management of Hyperpigmentation Disorder

26 citations , December 2022 in “Molecules”

This review discusses various nanotechnology-based strategies for managing melasma and reports no new clinical results, highlighting the potential of innovative drug delivery systems in treating hyperpigmentation.

research Hypopigmentation in frontal fibrosing alopecia

23 citations , May 2017 in “Journal of the American Academy of Dermatology”

This study found that patients with frontal fibrosing alopecia had lower epidermal melanocyte counts and reduced epidermal thickness compared to lichen planopilaris patients and controls, suggesting a link with hypopigmentation.

research Localised Skin Hyperpigmentation as a Presenting Symptom of Vitamin B12 Deficiency Complicating Chronic Atrophic Gastritis

5 citations , August 2015 in “Sultan Qaboos University medical journal”

This case report highlights an atypical presentation of vitamin B12 deficiency in a 28-year-old man with reversible symptoms including localized hand hyperpigmentation and megaloblastic anemia, resolved after B12 supplementation.

research Erythromelanosis follicularis faciei et colli with reticulated hyperpigmentation of the extremities

3 citations , August 2017 in “Clinical case reports”

A rare skin condition causes red and dark patches on the face and limbs.

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