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GlossaryHydroquinone

skin-lightening agent used to treat hyperpigmentation

Hydroquinone is a skin-lightening agent commonly used in dermatology to treat hyperpigmentation conditions such as melasma, age spots, and acne scars. It works by inhibiting the enzyme tyrosinase, which is essential for the production of melanin, the pigment responsible for skin color.

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research A Pilot Study for Triple Combination Therapy with a Low-Fluence 1064 nm Q-Switched Nd:YAG Laser, Hydroquinone Cream, and Oral Tranexamic Acid for Recalcitrant Riehl’s Melanosis

36 citations, June 2016 in “Journal of dermatological treatment”

The combination therapy significantly improved Riehl’s melanosis in patients without serious side effects.

research Diagnostic Utility of Dermatoscopy in Hydroquinone-Induced Exogenous Ochronosis

34 citations, February 2012 in “International Journal of Dermatology”

Dermatoscopy can help identify hydroquinone-induced skin issues, avoiding invasive biopsies.

research The Effect of Butin on the Vitiligo Mouse Model Induced by Hydroquinone

23 citations, March 2017 in “PTR. Phytotherapy research/Phytotherapy research”

Butin is effective in treating vitiligo in mice.

research Co-Drug Strategy for Promoting Skin Targeting and Minimizing the Transdermal Diffusion of Hydroquinone and Tranexamic Acid

21 citations, September 2013 in “Current medicinal chemistry”

HAC and BAC improve skin targeting and reduce diffusion without causing irritation.

research The Risk of Hydroquinone and Sunscreen Over-Absorption via Photodamaged Skin Is Not Greater in Senescent Skin Compared to Young Skin: Nude Mouse as an Animal Model

18 citations, May 2014 in “International journal of pharmaceutics”

Aging and sun damage do not increase the skin's absorption of certain sunscreens and drugs.

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