Hydroquinone
Research
20 / 432 resultsresearch Effects of Skin Lightening Cream Agents – Hydroquinone and Kojic Acid, on the Skin of Adult Female Experimental Rats
This study found that hydroquinone caused structural damage to the skin of rats, while aloe vera reduced this damage, suggesting potential concerns for its use in skin lightening creams.
research The First Clinical Experience on Efficacy of Topical Flutamide on Melasma Compared with Topical Hydroquinone: A Randomized Clinical Trial
This study observed that topical flutamide may be as effective as hydroquinone for treating melasma, with a trend towards greater improvement and patient satisfaction, but recommends further research before clinical use.
research A Pilot Study for Triple Combination Therapy with a Low-Fluence 1064 nm Q-Switched Nd:YAG Laser, Hydroquinone Cream, and Oral Tranexamic Acid for Recalcitrant Riehl’s Melanosis
This study found that a combination of low-fluence Q-switched 1064 nm Nd:YAG laser, hydroquinone cream, and oral tranexamic acid showed promising results for Riehl’s melanosis in Asian patients, with no serious adverse events reported.
research Diagnostic Utility of Dermatoscopy in Hydroquinone-Induced Exogenous Ochronosis
This study found that exogenous ochronosis from hydroquinone use in melasma treatment has distinctive dermatoscopic features that may aid in diagnosis without needing a biopsy.
research The Effect of Butin on the Vitiligo Mouse Model Induced by Hydroquinone
This study in mice found that butin, a component of Vernonia anthelmintica, increased melanin production and related proteins while reducing oxidative stress markers in a model of hydroquinone-induced vitiligo, suggesting support for its traditional use against this condition.
research Co-Drug Strategy for Promoting Skin Targeting and Minimizing the Transdermal Diffusion of Hydroquinone and Tranexamic Acid
This study found that co-drugs synthesized from hydroquinone and tranexamic acid improved skin targeting and deposition, with reduced irritation and enhanced efficacy for treating hyperpigmentation.
research The Risk of Hydroquinone and Sunscreen Over-Absorption via Photodamaged Skin Is Not Greater in Senescent Skin Compared to Young Skin: Nude Mouse as an Animal Model
This study found that UVA and UVB exposure increased hydroquinone and sunscreen absorption in nude mouse skin, with less absorption enhancement observed in more lipophilic sunscreens.
research Therapeutic Effects of Topical Mycophenolate Mofetil on Hydroquinone-Induced Depigmentation in Guinea Pigs and Mice
This study found that mycophenolate mofetil can enhance skin pigmentation in vitiligo models by activating the WNT signaling pathway and increasing melanin-related gene expression.
research An Open-Label Comparative Study on the Effects of Platelet-Rich Plasma Therapy with Hydroquinone 4% Versus Hydroquinone 4% Alone in Melasma
This study found that combining platelet-rich plasma with 4% hydroquinone was more effective in reducing melasma symptoms than using hydroquinone alone.
research Impact of Cosmetic Products with Hydroquinone on the Measure of Capillary Blood Sugar in Diabetic Senegalese Women: Case Control Study
This study aimed to assess how hydroquinone-based body milks affect blood glucose levels in diabetic women in Senegal but does not provide new results.
research Comparative Evaluation for the Efficacy and Tolerance of Two Skin Products Containing Either Hydroquinone or Emblica Extract with Kojic Acid in Female Subjects with Facial Dyschromia
Both skin products were equally effective in improving facial discoloration and skin quality.
research Lymphocytic Infiltration of the Skin Jessner-Kanof After Treatment With a Hydroquinone-Containing Bleaching Cream
research Skin Permeation of Small-Molecule Drugs, Macromolecules, and Nanoparticles Mediated by a Fractional Carbon Dioxide Laser: The Role of Hair Follicles
This study found that fractional laser treatment significantly enhances the penetration and targeting of certain permeants, such as imiquimod and FD, to skin follicles, but not hydroquinone.
research Solar-Induced Postinflammatory Hyperpigmentation After Laser Hair Removal
This report describes a case where solar-induced postinflammatory hyperpigmentation following laser hair removal was treated with a combination of topical treatments and serial TCA peels, resulting in only slight improvement.
research Vesicles: Potential Nano Carriers for the Delivery of Skin Cosmetics
This review discusses the research and development of vesicular carriers to enhance the delivery and effectiveness of active ingredients in cosmetic products, reporting no new clinical results.
research Glycine Inhibits Melanogenesis in Vitro and Causes Hypopigmentation in Vivo
This study found that glycine treatment inhibited melanogenesis in B16F0 melanoma cells and reduced melanin content in C57BL/6J mice by down-regulating tyrosinase protein levels.
research Pigmentation and Pregnancy: A Study on Skin Changes
This review discusses the effects of pregnancy on melanocytic nevi and reports no new clinical results; it suggests that changing nevi during pregnancy should be evaluated similarly to those in nonpregnant patients.
research 1927 Nm Thulium Laser Successfully Treats Post-Inflammatory Hyperpigmentation in Skin of Color
This study found that using a nonablative 1927 nm wavelength laser followed by hydroquinone cream is safe and effective for treating postinflammatory hyperpigmentation in patients with dark skin types.
research Topical And Systemic Therapies In Melasma: A Systematic Review
In this study, the researchers highlighted the availability of new topical and systemic agents with varied mechanisms for treatment, emphasizing that the choice of agent should be tailored to individual needs and the options available in different countries.
research Safety of Skin Care Products During Pregnancy
This article suggests that most topical treatments for acne and unwanted hair growth are safe to use during pregnancy, except for hydroquinone and tretinoin, due to low systemic absorption.