Glycine Inhibits Melanogenesis in Vitro and Causes Hypopigmentation in Vivo

January 2007 in “ Biological & pharmaceutical bulletin ”

Masago Ishikawa, Ichiro Kawase, Fumio Ishii

glycine melanogenesis B16F0 melanoma cells hair follicle melanogenesis C57BL/6J mice α-MSH tyrosinase melanin kojic acid hydroquinone

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Glycine →

Hydroquinone →

Studysummary This study found that glycine treatment inhibited melanogenesis in B16F0 melanoma cells and reduced melanin content in C57BL/6J mice by down-regulating tyrosinase protein levels.

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