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    Glycine Inhibits Melanogenesis in Vitro and Causes Hypopigmentation in Vivo

    January 2007 in “ Biological & pharmaceutical bulletin ”
    Masago Ishikawa, Ichiro Kawase, Fumio Ishii
    Studysummary This study found that glycine treatment inhibited melanogenesis in B16F0 melanoma cells and reduced melanin content in C57BL/6J mice by down-regulating tyrosinase protein levels.
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    Research cited in this study 5

    1. Oral Zinc Sulphate Causes Murine Hair Hypopigmentation And Is A Potent Inhibitor Of Eumelanogenesis In Vivo British journal of dermatology/British journal of dermatology, Supplement · 2006
    2. Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    3. Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    4. Hair Depigmentation Is a Biological Readout for Pharmacological Inhibition of KIT in Mice and Humans Journal of Pharmacology and Experimental Therapeutics · 2003
    5. Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993