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    Glossary Tyrosinase

    enzyme crucial for melanin production in skin and hair

    Tyrosinase is an enzyme that plays a crucial role in the production of melanin, the pigment responsible for the color of skin, hair, and eyes. It catalyzes the oxidation of tyrosine, an amino acid, into dopaquinone, which then undergoes further reactions to form melanin. This enzyme is significant in understanding conditions like albinism and vitiligo, where melanin production is affected.

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    1. Tyrosinase inhibition due to interaction of homocyst(e)ine with copper: the mechanism for reversible hypopigmentation in homocystinuria due to cystathionine beta-synthase deficiency. PubMed · 1995 · 74 citations
    2. Tyrosine kinase inhibition and grey hair The Lancet · 2003 · 59 citations
    3. Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle PloS one · 2015 · 31 citations
    4. The antimycotic agent clotrimazole inhibits melanogenesis by accelerating ERK and PI3K-/Akt-mediated tyrosinase degradation Experimental Dermatology · 2015 · 15 citations
    5. Screening of Tyrosinase, Xanthine Oxidase, and α-Glucosidase Inhibitors from Polygoni Cuspidati Rhizoma et Radix by Ultrafiltration and HPLC Analysis Molecules · 2023 · 12 citations
    6. Biotransformation of Finasteride by Ocimum sanctum L., and tyrosinase inhibitory activity of transformed metabolites: Experimental and computational insights Steroids · 2014 · 3 citations
    7. Plant‐Derived Monomers for Grey Hair Reversal Through Upregulation of Melanogenesis and Tyrosinase Activity Journal of Cellular and Molecular Medicine · 2025 · 1 citations
    8. Red pomegranate (Punica granatum L.) peel extract mud mask formulation and tyrosinase-inhibition activity test JURNAL ILMU KEFARMASIAN INDONESIA · 2024
    9. Tyrosine Kinase Inhibitors – A Review on Pharmacology, Metabolism and Side Effects Current drug metabolism · 2009 · 508 citations
    10. Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases Frontiers in immunology · 2019 · 88 citations
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    1. L-Tyrosine HCL
    2. Acetyl Tyrosine

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