Oral Zinc Sulphate Causes Murine Hair Hypopigmentation And Is A Potent Inhibitor Of Eumelanogenesis In Vivo

June 2006 in “ British journal of dermatology/British journal of dermatology, Supplement ”

Przemysław M. Płonka, Bori Handjiski, Dominika Michalczyk, Małgorzata Popik, Ralf Paus

zinc sulphate hair hypopigmentation eumelanogenesis eumelanin pigmentation disorders zinc sulfate hair lightening melanin production pigment disorders

TLDR Oral zinc sulphate reduces dark hair color in mice.

The study investigated the effects of oral zinc sulphate on hair pigmentation in mice and found that it caused significant hair hypopigmentation. The researchers concluded that zinc sulphate is a potent inhibitor of eumelanogenesis in vivo, meaning it effectively reduces the production of eumelanin, the pigment responsible for dark hair coloration. This finding suggested potential implications for understanding hair pigmentation processes and developing treatments for pigmentation disorders.

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Oral Zinc Sulphate Causes Murine Hair Hypopigmentation And Is A Potent Inhibitor Of Eumelanogenesis In Vivo

Research cited in this study

research Zinc as an Ambivalent but Potent Modulator of Murine Hair Growth In Vivo: Preliminary Observations

research A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice

research Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production

research Reversal of Hair Loss Following Vertical Gastroplasty When Treated with Zinc Sulfate

research Melanogenesis During the Anagen-Catagen-Telogen Transformation of the Murine Hair Cycle

research Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth

research Coarse to Fine Hair Conversion Induced by Zinc in C57/6J Mice

research Alopecia Induced in Young Mice by Exposure to Excess Dietary Zinc

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