research Downregulation of Nuclear Factor-KappaB Activation in Human Keratinocytes by Melanogenesis Inhibitors
Melanogenesis inhibitors like kojic acid and niacinamide can reduce inflammation and pigment production in skin cells.
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5 / 295 results research Comparative Evaluation for the Efficacy and Tolerance of Two Skin Products Containing Either Hydroquinone or Emblica Extract with Kojic Acid in Female Subjects with Facial Dyschromia
Both skin products were equally effective in improving facial discoloration and skin quality.
research Red Pomegranate (Punica Granatum L.) Peel Extract Mud Mask Formulation and Tyrosinase-Inhibition Activity Test
This study investigated the effects of varying kaolin base concentrations on mud mask formulations containing red pomegranate peel extract, known for its tyrosinase-inhibiting properties due to gallic and ellagic acids. Three formulations with kaolin concentrations of 19.5%, 22.5%, and 26.3% were tested for organoleptic properties, homogeneity, spreadability, viscosity, pH, and drying time. Formula 2, with a 22.5% kaolin base, showed optimal results, including a spreadability of 20.5863 cm², viscosity of 16040 cPs, pH of 5.86, and a drying time of 16.67 minutes. The tyrosinase inhibition activity was measured using ELISA, with IC50 values of 31.64 μg/mL for kojic acid, 155.49 μg/mL for the extract, and 276.15 μg/mL for the preparation. Significant differences in viscosity, pH, and drying time were observed with varying kaolin concentrations (p<0.05).
research Glycine Inhibits Melanogenesis in Vitro and Causes Hypopigmentation in Vivo
Glycine reduces skin pigmentation by lowering melanin production.
research Central Centrifugal Cicatricial Alopecia Gene Expression Analysis Revealed Cholesterol, Fatty Acid, and Mast Cell Pathways
Targeting cholesterol, fatty acids, fibrosis, and mast cells may help treat CCCA.
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