36 citations,
June 2016 in “Journal of dermatological treatment” The combination therapy significantly improved Riehl’s melanosis in patients without serious side effects.
34 citations,
February 2012 in “International Journal of Dermatology” Dermatoscopy can help identify hydroquinone-induced skin issues, avoiding invasive biopsies.
23 citations,
March 2017 in “PTR. Phytotherapy research/Phytotherapy research” Butin is effective in treating vitiligo in mice.
21 citations,
September 2013 in “Current medicinal chemistry” HAC and BAC improve skin targeting and reduce diffusion without causing irritation.
18 citations,
May 2014 in “International journal of pharmaceutics” Aging and sun damage do not increase the skin's absorption of certain sunscreens and drugs.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Using skin lightening products with hydroquinone can increase blood sugar levels in diabetic women.
February 2009 in “Journal of the American Academy of Dermatology” Both skin products were equally effective in improving facial discoloration and skin quality.
20 citations,
December 2006 in “Archives of dermatology” 10 citations,
June 2011 in “PubMed” Most skin care products are safe during pregnancy, but avoid hydroquinone and tretinoin.
January 2022 in “International Journal of Nutrology” Diet and nutrients, including lycopene from tomatoes and hydroquinone from wheat, can help control melasma, a skin condition.
July 1996 in “Hair transplant forum international” Using tretinoin and hydroquinone can speed up the fading of skin pigmentation.
43 citations,
November 2012 in “Pharmaceutical research” Fractional CO2 laser treatment significantly boosts drug and nanoparticle skin absorption, especially through hair follicles.
31 citations,
February 1999 in “Dermatologic surgery” Sun exposure after laser hair removal can cause skin darkening, which is hard to treat and requires avoiding UV light.
21 citations,
July 2017 in “Journal of Cosmetic and Laser Therapy” Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.
19 citations,
January 2007 in “Biological & pharmaceutical bulletin” Glycine reduces skin pigmentation by lowering melanin production.
15 citations,
December 2016 in “Obstetrics & Gynecology” Most skin changes during pregnancy are harmless and moles don't significantly change, but many women experience pigmentation changes due to hormones and sun exposure.
10 citations,
January 1967 in “PubMed” Oral contraceptives often cause melasma and other skin issues.
7 citations,
April 2011 in “Expert review of dermatology” The document concludes that patients with skin of color need specialized dermatological care and education to manage unique skin conditions effectively.
7 citations,
March 1990 in “Pigment Cell Research” Certain chemicals cause hair graying in black mice but not yellow mice.
5 citations,
August 2014 in “Dermatologic surgery” Advanced fluorescence technology effectively treats skin discoloration from certain creams.
2 citations,
October 2021 in “Clinical and experimental dermatology” Cyperus rotundus essential oil effectively treats underarm darkening, reduces inflammation, and slows hair growth.
1 citations,
January 2015 in “Journal of Pigmentary Disorders” Treating melasma in men is difficult, especially for the deeper skin layers, and may need more than just topical treatments.
1 citations,
January 2013 in “Springer eBooks” Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.
January 2023 in “Indian journal of pharmacy practice” Over-the-counter cosmetic creams can cause skin damage on the face that is visible under dermoscopy and confirmed by tissue analysis.
Melanin-rich skin has unique challenges in diagnosing and treating skin diseases.
February 2009 in “Springer eBooks” Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.
May 2004 in “International Journal of Cosmetic Science” Melanogenesis inhibitors like kojic acid and niacinamide can reduce inflammation and pigment production in skin cells.
New treatments for skin diseases in 1979 showed promising results with fewer side effects.
August 1998 in “Dermatologic Surgery” Use steroid creams without parabens and educate on hair transplant techniques to improve cosmetic surgery outcomes.
56 citations,
December 1978 in “The Journal of Dermatologic Surgery and Oncology” Transplanting small skin grafts can successfully repigment leukoderma.