An Open-Label Comparative Study on the Effects of Platelet-Rich Plasma Therapy with Hydroquinone 4% Versus Hydroquinone 4% Alone in Melasma

    January 2024 in “ Dermatology Review ”
    Muhammad Rawish Siddiqui
    Image of study
    TLDR Combining PRP with hydroquinone is more effective for treating melasma than using hydroquinone alone.
    This study involving 112 patients compared the effectiveness of platelet-rich plasma (PRP) combined with 4% hydroquinone versus 4% hydroquinone alone in treating melasma. Group A, which received PRP and hydroquinone, showed a greater reduction in the modified Melasma Area and Severity Index (mMASI) score, from 4.04 to 1.53, compared to Group B, which decreased from 3.89 to 2.26. Group A also reported higher patient satisfaction and a statistically significant better response, with 32.1% showing excellent improvement compared to 12.5% in Group B. The study concluded that the combination of PRP and hydroquinone is more effective than hydroquinone alone for melasma treatment, although further research with larger sample sizes is recommended.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 108 results

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 year ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Platelet rich plasma treatment

      in Treatment  6 upvotes 1 year ago
      A 27-year-old male experienced rapid hair loss after dengue fever, which activated a balding gene. The doctor suggested platelet-rich plasma treatment for hair regrowth.

      community platelet rich plasma experiences/thoughts?

      in Treatment  3 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 2 years ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  13 upvotes 2 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

    Similar Research

    5 / 1000+ results