Platelet-Rich Plasma in Melasma: A Systematic Review

    October 2021 in “ Dermatologic Surgery ”
    Rashmi Sarkar, Meenakshi Gupta
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    TLDR Platelet-rich plasma (PRP) can significantly improve melasma, a skin pigmentation disorder, but may not add benefits when used with certain other treatments.
    The systematic review analyzed seven studies on the efficacy and safety of platelet-rich plasma (PRP) in treating melasma, a common hyperpigmentation disorder. Most studies showed significant improvement in melasma when using intradermal injections of PRP. Microneedling mediated delivery of PRP also yielded good results. However, one study found no additional benefit of PRP in patients treated with topical tranexamic acid, and another found no benefit of intense pulsed light in patients treated with intradermal PRP. The review concluded that PRP inhibits melanin synthesis through various components acting through several mechanisms, demonstrating a moderate grade of recommendation according to the Oxford Center for Evidence-Based Medicine 2011 standards.
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      community Do Platelet-rich plasma, PRP work?

      in Research/Science  13 upvotes 1 year ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 month ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Why can't you drink caffeine after PRP?

      in Treatment  9 upvotes 2 years ago
      The conversation discusses avoiding caffeine after Platelet-Rich Plasma (PRP) treatment for hair loss because caffeine is a vasoconstrictor, which can reduce blood flow and hinder the healing process that PRP aims to promote.

      community I just made my own PRP - DIY PRP

      in Research/Science  548 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

      community Anyone have PRP/Exosome results to share?

      in Treatment  3 upvotes 1 year ago
      Considering alternative treatments to hair loss, such as platelet-rich plasma (PRP) and exosome therapy, instead of using medications like minoxidil, finasteride/dutasteride.

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