Platelet-Rich Plasma Is a Promising Therapy for Melasma
May 2021
in “
Journal of Cosmetic Dermatology
”
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Studysummary This review discusses the potential use of platelet-rich plasma for treating melasma, suggesting its effectiveness but noting the need for more extensive studies to confirm these findings.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Platelet-rich plasma (PRP) therapy is being recognized as a potential treatment for melasma, a skin condition that causes brown-gray patches. PRP contains growth factors like TGF-β that may reduce melanin production by inhibiting tyrosinase and related proteins, and it also enhances collagen synthesis, which can improve skin texture. A systematic review of the literature included 6 studies that met the criteria, suggesting PRP's effectiveness as a standalone or adjuvant therapy with few side effects. However, the review calls for more extensive randomized controlled trials to definitively confirm PRP's efficacy in treating melasma. The review does not provide the number of participants in the studies.
