Progress in the Use of Platelet-Rich Plasma in Aesthetic and Medical Dermatology

August 2020 in “ PubMed ”

Mao-Ying Lin, Chih-Yuan Lin, Sindy Hu, Wen-Hung Chung

platelet-rich plasma PRP androgenic alopecia alopecia areata chronic vitiligo melasma inflammatory nail disorders psoriasis hair density hair thickness

TLDR Platelet-rich plasma (PRP) is effective in treating various skin conditions and improving hair density, thickness, and patient satisfaction, with lower relapse rates for Alopecia Areata.

Three years ago, a review titled "Progress in the Use of Platelet-rich Plasma in Aesthetic and Medical Dermatology" discussed the use of platelet-rich plasma (PRP) in treating various dermatological conditions. PRP, a biological product derived from the plasma fraction of autologous blood, was found to be effective in skin rejuvenation, androgenic alopecia, alopecia areata, chronic vitiligo, melasma, inflammatory nail disorders, and psoriasis. PRP treatments showed improvements in hair density, thickness, and patient satisfaction. For Alopecia Areata, PRP injections had significantly lower relapse rates compared to traditional therapies. However, more detailed studies were suggested to standardize PRP preparation and optimize treatment methods.

View this study on pubmed.ncbi.nlm.nih.gov →

Discuss this study in the Community →

Research cited in this study

21 / 21 results

research Evaluation of Platelet-Rich Plasma vs Intralesional Steroid in Treatment of Alopecia Areata

19 citations, May 2019 in “Journal of Cosmetic Dermatology”

Platelet-rich plasma is a safe and effective treatment for hair loss, with fewer relapses than steroid treatment.

research Effect of Platelet-Rich Plasma Injection for Rejuvenation of Photoaged Facial Skin

51 citations, November 2018 in “JAMA Dermatology”

PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.

research Commentary on the Use of Platelet-Rich Plasma in Cicatricial Alopecia

3 citations, September 2018 in “Dermatologic Surgery”

Platelet-Rich Plasma (PRP) can improve hair loss in cicatricial alopecia cases, but treatment must be ongoing and results vary among patients.

Introducing Platelet-Rich Stroma: Platelet-Rich Plasma and Stromal Vascular Fraction Combined for the Treatment of Androgenetic Alopecia

research Introducing Platelet-Rich Stroma: Platelet-Rich Plasma and Stromal Vascular Fraction Combined for the Treatment of Androgenetic Alopecia

40 citations, March 2018 in “Aesthetic Surgery Journal”

New treatment combining PRP and SVF increases hair density in 6-12 weeks for androgenetic alopecia patients.

research Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

24 citations, January 2018 in “Journal of Visualized Experiments”

PRP injections effectively promote hair growth in androgenetic alopecia patients.

research Alopecia and Platelet-Derived Therapies

23 citations, November 2017 in “Stem cell investigation”

Platelet lysate is more effective than activated autologous platelet-rich plasma or saline in improving hair growth after hair restoration surgery.

research Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma for Treating Androgenic Alopecia

24 citations, November 2017 in “Aesthetic Plastic Surgery”

All types of Platelet-Rich Plasma (PRP) can treat hair loss, but homologous PRP works best due to its higher platelet count and growth factors from multiple donors.

research A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification

348 citations, July 2017 in “Skin appendage disorders”

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

research Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia

3 citations, May 2017 in “Dermatologic Surgery”

PRP may help treat female hair loss, but more research needed.

The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study

research The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study

52 citations, May 2017 in “Journal of Cosmetic Dermatology”

PRP injections improve hair density and thickness in women with hair loss.

research Platelet-Rich Plasma Versus Minoxidil 5% in Treatment of Alopecia Areata: A Trichoscopic Evaluation

62 citations, October 2016 in “Dermatologic Therapy”

PRP more effective than minoxidil 5% for treating alopecia areata.

research Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia

87 citations, September 2016 in “Dermatologic Surgery”

PRP shows potential for treating female hair loss, but more research needed.

research Efficacy of Platelet-Rich Plasma in the Treatment of Androgenetic (Male-Patterned) Alopecia: A Pilot Randomized Controlled Trial

61 citations, September 2016 in “Journal of Cosmetic and Laser Therapy”

Platelet-rich plasma (PRP) was found not effective in treating male-patterned hair loss.

research Autologous Platelet-Rich Plasma for the Treatment of Pattern Hair Loss

42 citations, May 2016 in “American Journal of Clinical Dermatology”

Using platelet-rich plasma, which is full of growth factors, can help treat pattern hair loss.

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations, September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

research Successful Treatment of Corticosteroid-Resistant Ophiasis-Type Alopecia Areata with Platelet-Rich Plasma

30 citations, August 2015 in “JAAD case reports”

Platelet-rich plasma (PRP) injections successfully treated a woman's steroid-resistant hair loss, causing hair to regrow within a month.

research Role of Platelet-Rich Plasma in Chronic Alopecia Areata: Our Centre Experience

61 citations, January 2015 in “Indian Journal of Plastic Surgery”

Platelet-rich plasma treatment could potentially be an effective way to treat chronic alopecia areata with minimal side effects.

research Therapeutic Efficacy of Autologous Platelet-Rich Plasma and Polydeoxyribonucleotide on Female Pattern Hair Loss

54 citations, December 2014 in “Wound Repair and Regeneration”

PRP injections may improve hair thickness and density in female hair loss patients.

A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations, April 2013 in “British Journal of Dermatology”

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

research The Effect of CD34+ Cell-Containing Autologous Platelet-Rich Plasma Injection on Pattern Hair Loss: A Preliminary Study

88 citations, December 2012 in “Journal of The European Academy of Dermatology and Venereology”

Injecting CD34+ cell-containing platelet-rich plasma into the scalp can improve hair count and thickness in people with pattern hair loss.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations, October 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

Related Community Posts Join

6 / 77 results

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community When are we getting a cure to hair loss?

in Chat 1 year ago

Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

community What else is good. Besides the big 3.

in Chat 36 upvotes 1 month ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 15 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community I just made my own PRP - DIY PRP

in Research/Science 549 upvotes 1 year ago

The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

Related Research

1 / 1 results

research Progress in the Use of Platelet-Rich Plasma in Aesthetic and Medical Dermatology

3 citations, August 2020 in “PubMed”

Platelet-rich plasma (PRP) is effective in treating various skin conditions and improving hair density, thickness, and patient satisfaction, with lower relapse rates for Alopecia Areata.