Effect of Platelet-Rich Plasma Injection for Rejuvenation of Photoaged Facial Skin

    November 2018 in “ JAMA Dermatology ”
    Murad Alam, Rosemara Hughart, Amanda Champlain, Amelia Geisler, Kapila V. Paghdal, Dennis Whiting, Josh A. Hammel, Amanda Maisel, Matthew J. Rapcan, Dennis P. West, Emily Poon
    Image of study
    TLDR PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.
    In a study conducted over nearly four years with 27 participants, researchers examined the effects of platelet-rich plasma (PRP) injections on photoaged facial skin. Participants received PRP injections on one cheek and saline injections on the other. While dermatologists did not notice a significant difference in photoaging scores between the treated and untreated sides, participants reported a significant improvement in skin texture and wrinkles on the PRP-treated side at 6 months after treatment. The study concluded that PRP may be beneficial for improving skin texture and wrinkles according to patient perceptions, despite the lack of observable differences by dermatologists. Adverse events were minor and temporary. Further research is suggested to explore the longevity and potential cumulative effects of PRP treatments.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 604 results

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 year ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Anyone have PRP/Exosome results to share?

      in Treatment  3 upvotes 3 years ago
      Considering alternative treatments to hair loss, such as platelet-rich plasma (PRP) and exosome therapy, instead of using medications like minoxidil, finasteride/dutasteride.

      community Went from almost balding to some this!

      in Progress Pictures  498 upvotes 2 years ago
      A user successfully regrew hair after nearly going bald by using oral finasteride, topical minoxidil, plasma injections, and mesotherapy over 9 months. They plan to try derma rolling and have an alarm set for taking medication, noting increased sexual drive as a side effect.

      community Shedding ALOT of hairs after 2nd session of PRap

      in Is this regrowth? 2 years ago
      After a second session of Platelet-Rich Plasma (PRP) treatment for hair regrowth, the user is experiencing increased shedding of thick and dark hairs and is concerned about whether this is temporary. They are seeking others' experiences with PRP, specifically regarding the duration of shedding and eventual positive outcomes.

      community Finasteride user thinking of going on Minoxidil: custom version vs. generic?

      in Minoxidil  7 upvotes 2 years ago
      A man in his 50s, who has been on Finasteride for 15 years, is considering adding a custom topical Minoxidil blend to his treatment due to recent hairline recession. He questions whether the custom blend is more effective than generic Minoxidil, expresses concerns about shedding and body hair growth, and seeks advice on application timing with styling products and whether to pursue other treatments like PRP or laser.

    Related Research

    1 / 1 results