Effect of Platelet-Rich Plasma Injection for Rejuvenation of Photoaged Facial Skin

    November 2018 in “ JAMA Dermatology ”
    Murad Alam, Rosemara Hughart, Amanda Champlain, Amelia Geisler, Kapila V. Paghdal, Dennis Whiting, Josh A. Hammel, Amanda Maisel, Matthew J. Rapcan, Dennis P. West, Emily Poon
    Image of study
    TLDR PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.
    In a study conducted over nearly four years with 27 participants, researchers examined the effects of platelet-rich plasma (PRP) injections on photoaged facial skin. Participants received PRP injections on one cheek and saline injections on the other. While dermatologists did not notice a significant difference in photoaging scores between the treated and untreated sides, participants reported a significant improvement in skin texture and wrinkles on the PRP-treated side at 6 months after treatment. The study concluded that PRP may be beneficial for improving skin texture and wrinkles according to patient perceptions, despite the lack of observable differences by dermatologists. Adverse events were minor and temporary. Further research is suggested to explore the longevity and potential cumulative effects of PRP treatments.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 79 results

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  13 upvotes 1 year ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 month ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Why can't you drink caffeine after PRP?

      in Treatment  9 upvotes 2 years ago
      The conversation discusses avoiding caffeine after Platelet-Rich Plasma (PRP) treatment for hair loss because caffeine is a vasoconstrictor, which can reduce blood flow and hinder the healing process that PRP aims to promote.

      community I just made my own PRP - DIY PRP

      in Research/Science  548 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

      community Anyone have PRP/Exosome results to share?

      in Treatment  3 upvotes 1 year ago
      Considering alternative treatments to hair loss, such as platelet-rich plasma (PRP) and exosome therapy, instead of using medications like minoxidil, finasteride/dutasteride.

    Related Research

    1 / 1 results