Evaluation of Platelet-Rich Plasma vs Intralesional Steroid in Treatment of Alopecia Areata

The study conducted in 2019 by Waleed Albalat and Howyda M. Ebrahim involved 80 patients with alopecia areata (AA), a condition causing non-scarring patchy hair loss. The patients were divided into two groups: Group I was treated with intralesional corticosteroids (ILCs) and Group II with platelet-rich plasma (PRP). Both treatments resulted in significant hair regrowth, with 65% of Group I and 72.5% of Group II showing improvement of more than 70%. Dermoscopic evaluation revealed significant regrowth of pigmented hair and a decrease in dystrophic hair in both groups. However, at a 6-month follow-up, 5% of patients in Group II had a relapse compared to 25% in Group I. The study concluded that PRP is a safe and promising treatment option for AA.