What’s New in Hair Loss

    March 2019 in “ Dermatologic Clinics ”
    Leopoldo Duailibe Nogueira Santos, Jerry Shapiro
    Image of study
    TLDR New treatments for hair loss show promise, but require more research on long-term effects and proper dosing.
    In 2019, the number of patients with frontal fibrosing alopecia had significantly increased. New drugs, such as retinoids, were being explored to halt hair loss progression. Alopecia areata was recognized as significantly impacting patient quality of life, with no FDA-approved treatment at the time. However, Janus Kinase (JAK) inhibitors showed promising results in treating alopecia areata. The side-effect profile of 5α-reductase was a concern for many patients. A study by Rakowska and colleagues found that hair loss progression was halted in 76% of patients using low-dose isotretinoin, 73% in the low-dose acitretin group, and 43% in the finasteride group. Despite these promising treatments, the long-term side effect profile, efficacy, initial regimen treatment, and maintenance dose still needed further evaluation.
    Discuss this study in the Community →

    Research cited in this study

    37 / 37 results

    Related Community Posts Join

    6 / 621 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 1 year ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

      community Hairloss all over body and head

      in Treatment  2 upvotes 23 hours ago
      A 25-year-old experiencing hair thinning all over the body and head, despite using minoxidil and having low vitamin D levels, is advised to seek a second opinion from a dermatologist specializing in hair loss. The likely diagnosis is diffuse alopecia areata, which may require treatment with a JAK inhibitor.

      community almost 6 months of progress :)

      in Progress Pictures  535 upvotes 1 year ago
      The user shared their 6-month hair regrowth progress using finasteride, minoxidil, biotin, and iron supplements, along with occasional microneedling and specific shampoos. They reported minimal side effects and no retrograde alopecia, attributing their success to a combination of treatments.

    Related Research

    11 / 11 results