TLDR Platelet-rich plasma may successfully treat lichen planopillaris, as shown by one patient's symptom regression.
The document discussed a novel treatment for lichen planopillaris (LPP) using platelet-rich plasma (PRP). LPP is challenging to treat due to irreversible hair follicle damage and low efficacy of existing treatments. The authors hypothesized that growth factors from PRP could halt LPP progression. They treated a patient who had not responded to previous treatments with a new PRP regimen. After six months, the patient experienced complete regression of itching and hair shedding. This was the first reported case of successful LPP treatment with PRP.
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26 citations
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March 2015 in “American journal of clinical dermatology” Topical clobetasol is recommended over mycophenolate mofetil for treating Lichen Planopilaris due to better safety and patient satisfaction.
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November 2014 in “Journal of the American Academy of Dermatology” Oral retinoids may help some patients with hard-to-treat lichen planopilaris, but more research is needed.
164 citations
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October 2014 in “Journal of Cutaneous and Aesthetic Surgery” PRP injections increase hair density and satisfaction in androgenetic alopecia patients.
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January 2014 in “Journal of the European Academy of Dermatology and Venereology” The critique highlights an error in a review about hair loss treatment, stressing the need for accurate information and caution due to poor evidence quality.
45 citations
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March 2013 in “European Journal of Plastic Surgery” Injecting platelet-rich plasma is a safe and effective way to treat hair loss.
251 citations
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November 2006 in “Plastic and reconstructive surgery/PSEF CD journals” Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.