Trichologic Response of Platelet-Rich Plasma in Androgenetic Alopecia Is Maintained During Combination Therapy

March 2018 in “ Journal of The American Academy of Dermatology ”

Anthony D. Ho, Kumar Sukhdeo, Kristen Lo Sicco, Jerry Shapiro

platelet-rich plasma androgenetic alopecia hair density hair thickness minoxidil finasteride combination therapy PRP AGA Rogaine Propecia

From the encyclopedia

Platelet-Rich Plasma →

growth factors taken from your blood and injected into your scalp to stimulate hair

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Finasteride →

Frontline, gold standard treatment for combatting androgenic alopecia

Studysummary This study found that platelet-rich plasma combined with other hair restoration therapies significantly increased hair density in patients with androgenetic alopecia, though it did not statistically affect hair shaft diameter.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This document is a compilation of summaries of various studies that investigated the effectiveness of platelet-rich plasma (PRP) therapy in treating androgenetic alopecia (AGA) in combination with other hair restoration therapies. The studies found that PRP therapy can increase hair density and thickness in AGA patients, and the positive effects are maintained during combination therapy with other hair restoration modalities such as minoxidil and finasteride. However, the studies had limitations such as small sample sizes and retrospective designs, and further research is needed to confirm the findings. Overall, PRP therapy can be a useful treatment option for AGA patients in dermatologic clinics.

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Research cited in this study

2 / 2 results

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations , April 2016 in “Dermatologic Surgery”

This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

270 citations , March 2012 in “Dermatologic Surgery”

This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.