TLDR Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.
In 2012, a study investigated the effects of activated platelet-rich plasma (PRP) on hair growth. The researchers found that PRP increased the proliferation of dermal papilla (DP) cells, stimulated certain signaling pathways, and upregulated growth factors, all of which are potent stimuli for hair growth. In an in vivo study, mice injected with PRP showed faster hair growth cycle transitions compared to control mice. The study also found that PRP increased the expression of certain proteins in cultured human DP cells, suggesting it stimulates hair growth by inducing the differentiation of stem cells into hair follicle cells. However, further studies were needed to investigate the mechanism of action and safety of PRP before it could be applied clinically.
51 citations,
February 2009 in “Journal of dermatological science” Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
41 citations,
January 2007 in “Journal of Korean Medical Science” Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.
251 citations,
October 2006 in “Plastic and reconstructive surgery/PSEF CD journals” Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.
3 citations,
April 2023 in “Dermatologica Sinica” PRP treatment may help with alopecia areata, especially in newer cases.
1 citations,
January 2017 in “Elsevier eBooks” The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.
April 2017 in “Al-Azhar Medical Journal” PRP is an effective and safe treatment for alopecia areata.
November 2023 in “Materials Today Bio” Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.
13 citations,
September 2020 in “International Journal of Molecular Sciences” PRP therapy and minoxidil combo works best for male hair loss.
October 2023 in “Bioactive Materials” The new hair loss treatment combining nitric oxide and minoxidil in a special carrier is effective for hair regrowth.
