Platelet-Rich Plasma in the Treatment of Alopecia Areata: A Retrospective Evaluation of 17 Patients

April 2023 in “ Dermatologica Sinica ”

Yusuf Kelleci, Fatma Aydın, Gökhan Şahin, Esra Pancar Yüksel

platelet-rich plasma alopecia areata SALT scores PRP AA

TLDR PRP treatment may help with alopecia areata, especially in newer cases.

This retrospective study evaluated the efficacy and safety of platelet-rich plasma (PRP) treatment in 17 patients with patch-type alopecia areata (AA). After three months, the Severity of Alopecia Tool (SALT) score significantly decreased from 6.82 ± 4.96 to 4.35 ± 4.58 (P = 0.01). Six patients (35.3%) had an excellent response, one had a good response, one had a partial response, and nine had no response. Excluding three chronic AA patients, the response rate increased to 64.3%. No severe side effects were observed, and only one patient experienced a relapse within 1 year. The study suggests PRP may be a beneficial treatment for AA, especially in patients with a shorter disease duration, but further research is needed to fully understand its mechanisms and efficacy.

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