Platelet-Rich Plasma in the Treatment of Alopecia Areata: A Retrospective Evaluation of 17 Patients

    April 2023 in “ Dermatologica Sinica ”
    Yusuf Kelleci, Fatma Aydın, Gökhan Şahin, Esra Pancar Yüksel
    TLDR PRP treatment may help with alopecia areata, especially in newer cases.
    This retrospective study evaluated the efficacy and safety of platelet-rich plasma (PRP) treatment in 17 patients with patch-type alopecia areata (AA). After three months, the Severity of Alopecia Tool (SALT) score significantly decreased from 6.82 ± 4.96 to 4.35 ± 4.58 (P = 0.01). Six patients (35.3%) had an excellent response, one had a good response, one had a partial response, and nine had no response. Excluding three chronic AA patients, the response rate increased to 64.3%. No severe side effects were observed, and only one patient experienced a relapse within 1 year. The study suggests PRP may be a beneficial treatment for AA, especially in patients with a shorter disease duration, but further research is needed to fully understand its mechanisms and efficacy.
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