Understanding Autoimmunity of Vitiligo and Alopecia Areata

    Jillian F. Rork, Mehdi Rashighi, John E. Harris
    Studysummary This review identifies shared interferon gamma-driven immune pathways in vitiligo and alopecia areata, revealing potential targets for new treatments, but reports no clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 16

    1. Familial Aggregation of Alopecia Areata Journal of the American Academy of Dermatology · 2016
    2. Rapid Skin Repigmentation on Oral Ruxolitinib in a Patient with Coexistent Vitiligo and Alopecia Areata Journal of the American Academy of Dermatology · 2015
    3. Topical Ruxolitinib for the Treatment of Alopecia Universalis JAMA dermatology · 2015
    4. Extensive Alopecia Areata Is Reversed by IL-12/IL-23p40 Cytokine Antagonism The Journal of Allergy and Clinical Immunology · 2015
    5. Functional Interpretation of Genome-Wide Association Study Evidence in Alopecia Areata Journal of Investigative Dermatology · 2015
    6. Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology · 2015
    7. Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib EBioMedicine · 2015
    8. Investigation of Oxidative Stress in Patients with Alopecia Areata and Its Relationship with Disease Severity, Duration, Recurrence, and Pattern Clinical and experimental dermatology · 2014
    9. The Autoimmune Basis of Alopecia Areata: A Comprehensive Review Autoimmunity reviews · 2014
    10. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    11. Alopecia Areata: An Evidence-Based Treatment Update American journal of clinical dermatology · 2014
    12. Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis Journal of Investigative Dermatology · 2014
    13. Vitiligo and Alopecia Areata: Apples and Oranges? Experimental Dermatology · 2013
    14. Oxidative Stress in Alopecia Areata: A Case-Control Study American Journal of Clinical Dermatology · 2013
    15. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012
    16. Alopecia Areata Update Journal of The American Academy of Dermatology · 2010