Search

for
Search:

Did you mean Preclinical Studies?

Glossary Preclinical Studies

laboratory and animal tests before human clinical trials

Preclinical Studies, also known as Preclinical Research or Preclinical Testing, are a phase of research conducted before clinical trials in humans. These studies involve laboratory experiments and animal testing to evaluate the safety, efficacy, and biological activity of a new drug or treatment. The goal is to gather enough data to determine whether the treatment is safe and promising enough to move on to human trials.

Related Terms

Research

5 / 1000+ results

research Clinical dose ranging studies with finasteride, a type 2 5α-reductase inhibitor, in men with male pattern hair loss

46 citations , October 1999 in “Journal of The American Academy of Dermatology”

This study found that finasteride at 1 mg/day was the most effective dose for treating male pattern hair loss, with similar efficacy to 5 mg/day and better results than lower doses.

Substances Declared as Active Ingredients in Topical Anti-Hair Loss Products: A Review of the Evidence for Their Effectiveness in Light of Clinical Studies

research Substances declared as active ingredients in topical anti-hair loss products – a review of the evidence for their effectiveness in light of clinical studies

June 2026 in “Homo Politicus (Academy of Humanities and Economics in Lodz)”

The effectiveness of ingredients in anti-hair loss products varies, and clinical trials are crucial to determine their success.

research Clinical Studies Using Topical Melatonin

May 2024 in “International journal of molecular sciences”

This review examined clinical studies on topical melatonin for skin protection and found strong evidence that it effectively prevents skin damage from radiation, but noted limited clear evidence for its anti-aging and hair growth benefits due to study design limitations and combined treatments.

research Nutritional Clinical Studies in Dermatology

6 citations , January 2011 in “Springer eBooks”

Nutrition is important for skin health, and changing diet can help prevent and treat skin diseases.

research CLINICAL AND LABORATORY STUDIES ON EMACIATION AND ILL-THRIFTINESS IN CATTLE AT ASWAN GOVERNORATE

1 citations , January 2014 in “Assiut Veterinary Medical Journal/Maǧallaẗ Asyūṭ al-ṭibiyyaẗ al-baytariyyaẗ”

This study in Aswan governorate reported that emaciated cattle showed decreased blood cell counts and serum minerals, as well as elevated liver enzymes, possibly associated with parasitic infections.

View more "clinical studies" in research →

Learn

10 / 801 results

learn KY19382

Are there clinical studies showing that KY19382 can regrow hair in androgenic alopecia? No clinical studies have proven KY19382 regrows hair in androgenic alopecia.

learn Follistatin

Are there any clinical studies supporting follistatin as a hair loss treatment? There is no controlled human trial showing follistatin treats hair loss; the published work is mouse and laboratory biology on the activin/follistatin signalling system, plus one small 2011 phase 1 injection study of a combination product, so follistatin remains experimental and unapproved.

learn Tofacitinib

What types of hair loss conditions are most commonly associated with tofacitinib use in clinical settings? Published studies link tofacitinib mainly to alopecia areata and its severe variants — as an off-label drug being studied for them, not as a cause of hair loss. The evidence is mostly small, open-label or retrospective, and relapse after stopping is commonly reported.

learn SCUBE3

Is SCUBE3 available in topical or injectable form, and how is it usually applied in studies? SCUBE3 is not available as a topical or injectable treatment and is not an approved medicine. In the published research it was delivered by microinjecting the recombinant protein into mouse skin and into cultured or grafted human follicles; there are no human clinical trials.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Caffeine

the stimulant you know and love can be used topically to stimulate hair

learn GT20029

research compound made to degrade androgen receptors in scalp

learn PP405

mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

learn Latanoprost

glaucoma medication with hair follicle stimulant effects

View more "clinical studies" in learn →

Community Join

5 / 1000+ results

community Finasteride/dutasteride/etcetera. Clinical opinions of 1 GP and 1 leading urologist + links to reliable studies.

8 upvotes 7 years ago

Finasteride is effective for treating male pattern baldness (MPB) with minimal side effects, and topical finasteride is similarly effective. Dutasteride is also effective but less understood, and Minoxidil is less effective than Finasteride.

community Any clinical study on cysteine alone for hair loss?

6 upvotes 1 year ago

The conversation discusses the lack of clinical studies on cysteine alone for hair loss, with the original poster already using medications like Minoxidil and finasteride. Suggestions include trying 2ddr as a growth stimulant, though concerns about side effects like gas are mentioned.

community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

15 upvotes 7 years ago

PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

community Joining clinical study for Clascoterone (Breezula)

in Research/Science 7 upvotes 1 year ago

The conversation is about a user considering joining a clinical study for Clascoterone (Breezula) after experiencing no results with topical finasteride and minoxidil, and side effects from oral finasteride. The user is seeking advice on clinical study participation and experiences.

community Are there any studies made showing percentage of dutasteride non-responders?

2 upvotes 1 year ago

The user discusses their experience with hair loss treatments, noting that finasteride seemed more effective than dutasteride, which did not suppress DHT as expected. They express concern about worsening hair condition after switching from finasteride to dutasteride.

View more "clinical studies" in community →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →