Reporting in Clinical Studies on Platelet-Rich Plasma Therapy Among All Medical Specialties: A Systematic Review of Level I and II Studies

    April 2021 in “ PLOS ONE ”
    J. Nazaroff, Sarah Oyadomari, Nolan J. Brown, Dean Wang
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    TLDR The review concluded that reporting on PRP therapy is often incomplete, leading to uncertainty about its effectiveness.
    This systematic review analyzed 132 Level I and II clinical studies on platelet-rich plasma (PRP) therapy across all medical specialties, with the majority conducted for musculoskeletal injuries. The review found that only 33% of the studies provided details on PRP processing or characteristics, and only 17% reported the leukocyte component. Overall, 61% of the studies found PRP to be favorable over control treatment. The authors concluded that there is a significant lack of uniformity in reporting PRP protocols and characteristics, which may contribute to the uncertainty of PRP within the medical community. They emphasized the need for more meticulous reporting of PRP protocols in human studies for proper evaluation of the therapy's efficacy.
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      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 year ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Anyone have PRP/Exosome results to share?

      in Treatment  3 upvotes 3 years ago
      Considering alternative treatments to hair loss, such as platelet-rich plasma (PRP) and exosome therapy, instead of using medications like minoxidil, finasteride/dutasteride.

      community Went from almost balding to some this!

      in Progress Pictures  498 upvotes 2 years ago
      A user successfully regrew hair after nearly going bald by using oral finasteride, topical minoxidil, plasma injections, and mesotherapy over 9 months. They plan to try derma rolling and have an alarm set for taking medication, noting increased sexual drive as a side effect.

      community Shedding ALOT of hairs after 2nd session of PRap

      in Is this regrowth? 2 years ago
      After a second session of Platelet-Rich Plasma (PRP) treatment for hair regrowth, the user is experiencing increased shedding of thick and dark hairs and is concerned about whether this is temporary. They are seeking others' experiences with PRP, specifically regarding the duration of shedding and eventual positive outcomes.

      community Finasteride user thinking of going on Minoxidil: custom version vs. generic?

      in Minoxidil  8 upvotes 2 years ago
      A man in his 50s, who has been on Finasteride for 15 years, is considering adding a custom topical Minoxidil blend to his treatment due to recent hairline recession. He questions whether the custom blend is more effective than generic Minoxidil, expresses concerns about shedding and body hair growth, and seeks advice on application timing with styling products and whether to pursue other treatments like PRP or laser.

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