Topical Ruxolitinib for the Treatment of Alopecia Universalis

    December 2015 in “ JAMA dermatology
    Brittany G. Craiglow, Daniel Tavares, Brett King
    TLDR Topical Ruxolitinib may safely treat severe hair loss.
    The document discussed the potential of topical Ruxolitinib as a treatment for Alopecia Universalis, a severe form of alopecia areata. While oral Janus kinase (JAK) inhibitors had been effective in treating these conditions, they carried risks of serious adverse effects. The study suggested that using a topical form of Ruxolitinib could mitigate these risks, offering a safer alternative for patients.
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      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

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      in Research/Science  10 upvotes 1 year ago
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