Topical Ruxolitinib for the Treatment of Alopecia Universalis

    December 2015 in “ JAMA dermatology
    Brittany G. Craiglow, Daniel Tavares, Brett King
    TLDR Topical Ruxolitinib may safely treat severe hair loss.
    The document discussed the potential of topical Ruxolitinib as a treatment for Alopecia Universalis, a severe form of alopecia areata. While oral Janus kinase (JAK) inhibitors had been effective in treating these conditions, they carried risks of serious adverse effects. The study suggested that using a topical form of Ruxolitinib could mitigate these risks, offering a safer alternative for patients.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 1000+ results

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 7 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community Ruxolitinib - Start of a case study

      in Research/Science  10 upvotes 1 year ago
      The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

      community Topical 5% Min - 2% Keto shampoo - 4 months update - 26M out

      in Is this regrowth?  10 upvotes 23 hours ago
      A 26-year-old male experiencing hair loss since 2020 is using topical 5% Minoxidil and 2% Ketoconazole shampoo for four months, still experiencing significant shedding. He is considering cutting his hair short and has not yet started DHT blockers like Finasteride or Dutasteride.

      community Topical Finasteride 2 year update

      in Progress Pictures  730 upvotes 2 days ago
      The user reported significant improvement in hair quality and stability using topical finasteride for two years, without side effects. They later added minoxidil, which may have further enhanced hair quality.

      community Sensitive liver, topical fin safe to try?

      in Finasteride  98 upvotes 5 days ago
      Topical finasteride is considered safer for the liver than oral finasteride due to less systemic absorption, but regular liver function tests are advised. The user is concerned about liver health due to a history of NAFLD and is exploring topical finasteride as a safer alternative.

    Related Research

    3 / 3 results