A Case of Topical Ruxolitinib Treatment Failure in Alopecia Areata

    June 2017 in “ Journal of cutaneous medicine and surgery ”
    Maya Deeb, Renée A. Beach
    Studysummary This study reports that topical ruxolitinib failed to induce hair growth in a 66-year-old patient with alopecia areata, highlighting the need to explore factors affecting treatment response and compare topical vs oral administration outcomes.
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    Research cited in this study 4

    1. Oral Ruxolitinib Induces Hair Regrowth in Patients with Moderate-to-Severe Alopecia Areata JCI insight · 2016
    2. Topical Ruxolitinib for the Treatment of Alopecia Universalis JAMA dermatology · 2015
    3. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    4. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010

    Related research 1

    1. Tofacitinib (Selective Janus Kinase Inhibitor 1 and 3): A Promising Therapy for the Treatment of Alopecia Areata: A Case Report of Six Patients International Journal of Trichology · 2018