A Case of Topical Ruxolitinib Treatment Failure in Alopecia Areata

    June 2017 in “ Journal of cutaneous medicine and surgery ”
    Maya Deeb, Renée A. Beach
    TLDR Topical ruxolitinib failed to regrow hair in a 66-year-old with alopecia areata.
    The document reported a case where topical ruxolitinib (0.6% cream) failed to induce hair growth in a 66-year-old patient with alopecia areata (AA). This contrasted with a previous success in a young patient with alopecia universalis (AU). The study highlighted the need to understand the factors contributing to variations in treatment response, including patient-specific intrinsic factors and treatment regimen-related extrinsic factors. It also suggested that oral administration of ruxolitinib might be more effective for severe cases of AA, AT, and AU compared to topical application.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 1000+ results

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 11 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community Ruxolitinib - Start of a case study

      in Research/Science  10 upvotes 1 year ago
      The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

      community Topical finasteride carrier vehicle

      in Finasteride/Dutasteride  1 upvotes 3 days ago
      The user is using a topical solution containing 1% finasteride and 5% minoxidil for hair loss, with water, glycerin, and PEG-40 hydrogenated castor oil as carrier agents. They are questioning if these ingredients are effective carriers after using the solution for three months.

      community Topical finasteride 0.025% shedding

      in Finasteride/Dutasteride  3 upvotes 1 week ago
      A user is experiencing increased hair shedding after using a homemade topical finasteride mixture with stemoxydine for six weeks. They are concerned about whether the low dose could cause shedding so early.

    Related Research

    1 / 1 results