A Case of Topical Ruxolitinib Treatment Failure in Alopecia Areata

    June 2017 in “ Journal of cutaneous medicine and surgery ”
    Maya Deeb, Renée A. Beach
    TLDR Topical ruxolitinib failed to regrow hair in a 66-year-old with alopecia areata.
    The document reported a case where topical ruxolitinib (0.6% cream) failed to induce hair growth in a 66-year-old patient with alopecia areata (AA). This contrasted with a previous success in a young patient with alopecia universalis (AU). The study highlighted the need to understand the factors contributing to variations in treatment response, including patient-specific intrinsic factors and treatment regimen-related extrinsic factors. It also suggested that oral administration of ruxolitinib might be more effective for severe cases of AA, AT, and AU compared to topical application.
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      community What else is good. Besides the big 3.

      in Chat  35 upvotes 1 year ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community Ruxolitinib - Start of a case study

      in Research/Science  10 upvotes 1 year ago
      The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

      community How come topical finasteride even works at all?

      in Finasteride/Dutasteride  31 upvotes 1 week ago
      Topical finasteride can effectively reduce scalp DHT by targeting local enzymes, despite less systemic impact compared to oral forms. Combining oral dutasteride with topical finasteride and minoxidil may enhance hair loss prevention, though evidence of its effectiveness is limited.

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      in Product  1 upvotes 1 week ago
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      community Topical Dutasteride Seems to Work

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