A Case of Topical Ruxolitinib Treatment Failure in Alopecia Areata

    June 2017 in “ Journal of cutaneous medicine and surgery ”
    Maya Deeb, Renée A. Beach
    TLDR Topical ruxolitinib failed to regrow hair in a 66-year-old with alopecia areata.
    The document reported a case where topical ruxolitinib (0.6% cream) failed to induce hair growth in a 66-year-old patient with alopecia areata (AA). This contrasted with a previous success in a young patient with alopecia universalis (AU). The study highlighted the need to understand the factors contributing to variations in treatment response, including patient-specific intrinsic factors and treatment regimen-related extrinsic factors. It also suggested that oral administration of ruxolitinib might be more effective for severe cases of AA, AT, and AU compared to topical application.
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      in Chat  34 upvotes 4 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community Ruxolitinib - Start of a case study

      in Research/Science  10 upvotes 9 months ago
      The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

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      in Update  1682 upvotes 1 week ago
      Topical minoxidil and oral finasteride can effectively improve hair growth and slow hair loss, though results may vary. Consistency is important for achieving significant improvement.

      community Topical Finasteride concetrations and amount applied

      in Treatment  10 upvotes 1 week ago
      Topical finasteride concentrations and application amounts are debated, with concerns that mainstream solutions may use arbitrary concentrations. A 0.25% solution with a specific application method is suggested as more appropriate than higher concentrations.

      community Topical Min Progress Oct 2024 - Feb 2025

      in Progress Pictures  276 upvotes 2 weeks ago
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