Frontal Fibrosing Alopecia: Clinical and Prognostic Classification

    April 2017 in “ JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology ”
    Ó.M. Moreno-Arrones, David Saceda‐Corralo, Pablo Fonda‐Pascual, Ana Rita Rodrigues-Barata, Diego Buendia‐Castaño, A. Alegre-Sánchez, Cristina Pindado‐­Ortega, M Molins, D. Perosanz, Gonzalo Segurado‐Miravalles, Pedro Jaén, Sergio Vañó‐Galván
    TLDR Researchers found three patterns of Frontal fibrosing alopecia, with Pattern III having the best prognosis after treatment.
    The study on frontal fibrosing alopecia (FFA) aimed to create a clinical and prognostic classification by analyzing differences in clinical presentation and evolution among patients. A retrospective analytical study was conducted on 242 female patients with a mean age of 61.4 years, classifying them into three clinical patterns: pattern I (linear) with 118 patients (48.8%), pattern II (diffuse) with 109 patients (45%), and pattern III (double line) with 15 patients (6.2%). A cohort of 106 patients treated with oral dutasteride and topical corticosteroid was followed for 12 months, achieving stabilization in 37.3% of cases. Pattern III patients exhibited less hairline recession and eyebrow involvement, indicating a better prognosis, while pattern II patients had the worst prognosis. The study's retrospective design was noted as a limitation.
    Discuss this study in the Community →

    Research cited in this study

    17 / 17 results

    Related Community Posts Join

    6 / 435 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community M18 - 7 Months on topical fin + min Not working for me

      in Finasteride/Dutasteride  92 upvotes 1 month ago
      Topical finasteride and minoxidil are not effective for the user, who is considering switching to oral treatments like finasteride or dutasteride. Many suggest oral medications are more effective, and some recommend additional treatments like microneedling and other topical solutions.

      community 9 months on Fin - no progress , should I get on Dutasteride?

      in Chat  10 upvotes 4 months ago
      The user has been using finasteride, minoxidil, and nizoral for hair loss but hasn't seen regrowth, only maintenance. They are considering switching to dutasteride, which is believed to be more effective, but are concerned about potential side effects.

      community Diffuse thinning is so brutal.

      in Styling  72 upvotes 1 year ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  82 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

    Similar Research

    5 / 1000+ results