Frontal fibrosing alopecia in postmenopausal women
January 2005
in “Journal of The American Academy of Dermatology”
TLDR Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.
From June 2000 to July 2003, a study involving 14 postmenopausal women aged 54 to 78 diagnosed with frontal fibrosing alopecia (FFA) found that FFA is characterized by hair follicle destruction due to an inflammatory lymphocytic infiltrate, particularly affecting intermediate and vellus-like follicles. The cause of the selective follicle involvement is unclear. Some patients experienced a halt in disease progression when treated with finasteride (2.5 mg/d), suggesting a potential role of androgens in FFA's pathogenesis, although the small sample size limits the statistical significance of this finding. FFA is distinct from lichen planus pilaris (LPP) due to its selective follicle involvement and may be related to fibrosing alopecia in a pattern distribution (FAPD), which also suggests androgens could be involved. However, the hormonal basis of FFA has not been definitively established.
View this study on jaad.org →
Cited in this study
research Histological features of peripilar signs associated with androgenetic alopecia
Peripilar signs can help diagnose androgenetic alopecia and reveal its cause.
research Post-menopausal frontal fibrosing alopecia
The document concludes that post-menopausal frontal fibrosing alopecia is a poorly understood condition that does not respond well to common treatments.
research Postmenopausal frontal fibrosing alopecia
Postmenopausal frontal fibrosing alopecia is a type of hair loss in postmenopausal women that may stop on its own but has no effective treatment.
research Frontal fibrosing alopecia associated with cutaneous lichen planus in a premenopausal woman
A premenopausal woman had hair loss and skin issues, treated with topical steroids.
research Female pattern hair loss
Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.
research Fibrosing Alopecia in a Pattern Distribution
Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.
research Postmenopausal frontal fibrosing alopecia: A frontal variant of lichen planopilaris
Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.
research Histopathology of non-scarring alopecia
The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
Related
research Feature characterization of scarring and non-scarring types of alopecia by multiphoton microscopy
Multiphoton microscopy can non-invasively tell apart scarring from non-scarring hair loss and could aid in treatment.
research Hair disorders
The document's conclusion cannot be provided because the document cannot be parsed.
research 대학병원 피부과 외래에 내원한 안드로겐 및 원형탈모증 환자에서의 대표적 Trichoscopic Finding에 대한 고찰
The document's conclusion cannot be summarized as it is not provided in a language I can understand.
research Evaluation of hair loss
research Androgenetic alopecia, trichotrophic substances, and histologic studies of the human scalp
Minoxidil promotes hair growth but exact mechanism is unknown.